摘要
目的分析引起医院多药耐药菌感染的各类影响因素及其关联强度和预防分值,为制定控制多药耐药菌感染的措施提供科学依据。方法取医院2013-2015年住院患者137 691例为研究对象,分析多药耐药菌感染率;采用自制的调查问卷调查相关的危险因素。结果多因素logistic回归分析显示手术、营养不良、住院时间长、使用抗菌药物、手卫生执行不到位、物表清洁不合格、空气消毒效果不合格、泌尿道插管、患肺部疾病、动静脉插管、放置引流管、使用呼吸机和使用激素为多药耐药菌感染的独立危险因素(P<0.05);其中动静脉插管、手术、使用呼吸机的病因分值比较高,手术、住院时间长和使用抗菌药物的患者归因分值较高。结论加强对手术、动静脉插管和使用呼吸机人群的管理和对住院患者严把手术适应证、缩短其住院天数和减少抗菌药物的使用对多药耐药菌感染的预防和控制具有重要意义。
OBJECTIVE To explore the influencing factors for multidrug-resistant organisms (MDROs) infections and observe their associated intensity and prevention score so as to provide scientific basis for control of the MDROs infections. METHODS A total of 137 691 patients who were hospitalized from 2013 to 2015 were recruited as the study objects, the incidence of MDROs infections was analyzed, and the related risk factors were investiga- ted by using self-designed questionnaires. RESULTS The multivariate logistic regression analysis showed that the independent risk factors for the MDROs infections included the surgery, malnutrition, long hospitalization dura- tion, use of antibiotics, poor execution of hand hygiene, unqualified cleaning of object surfaces, unqualified air dis- infection, urinary tract intubation, pulmonary diseases, arteriovenous intuhation, placement of drainage tube, use of ventilator, and use of hormones (P〈0.05). The etiology scores of arteriovenous intubation, surgery, and use of ventilator were relatively high, while the population attributable fractions of the surgery, long hospitalization duration, and use of antibiotics were relatively high. CONCLUSION It is of great significance to strengthen the management of the population who receive surgery and arteriovenous intubation and use ventilator, reduce the un- necessary surgeries, shorten the hospitalization duration, and decrease the use of antibiotics so as to prevent and control the MDROs infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2017年第8期1702-1705,共4页
Chinese Journal of Nosocomiology
关键词
多药耐药
医院感染
影响因素
Multidrug-resistant
Nosocomial infection
Influencing factor