摘要
目的了解多重耐药菌(MDROs)感染及细菌耐药性特征,为MDROs防控提供依据。方法收集2017年9月-2018年8月住院患者微生物标本的相关资料,就其MDROs和细菌耐药性进行分析。结果 7 686株菌中MDROs检出率为35. 3%,产超广谱β-内酰胺酶细菌(ESBLs),占47. 7%;耐碳青酶烯类鲍曼不动杆菌(CRAB)占22. 5%;标本以痰液为主占47. 7%,主要科室为急诊科(含急诊ICU)、神经外科(含神外ICU)和综合ICU,分别占14. 3%、13. 2%和10. 3%;金黄色葡萄球菌、无乳链球菌、粪肠球菌、肺炎链球菌和屎肠球菌仅对万古霉素、替加环素和利奈唑胺耐药率较低,大肠埃希菌、铜绿假单胞菌、鲍曼不动杆菌、肺炎克雷伯菌和嗜麦芽寡养单胞菌对常用药物普遍耐药。结论 MDROs检出率较高,主要类型为ESBLs和CRAB,主要检出标本为痰液,主要科室为含ICU的科室,常见细菌耐药严重,应开展MDROs精准感控,加强目标性监测和相关影响因素的防控。
Objective To understand the characteristics of multidrug-resistant organisms(MDROs)infection and bacterial resistance,so as to provide reference for prevention and control of MDROs.Methods Data of microbial specimens of hospitalized patients were collected from September 2017 to August 2018 and their MDROs and bacterial resistance were analyzed.Results The detection rate of MDROs was 35.3%in 7 686 strains.The main types of MDROs included extended-spectrumβ-lactamases-producing bacteria(ESBLs,47.7%),carbapenem-resistant Acinetobacter baumannii(CRAB,22.5%).The main source of MDROs specimens was sputum,accounting for 47.7%.The departments of MDROs specimens mainly came from emergency department(including emergency ICU),neurosurgery department(including neurosurgery ICU)and comprehensive ICU,accounting for 14.3%,13.2%and 10.3%respectively.Staphylococcus aureus,Streptococcus agalactiae,Enterococcus faecalis,Streptococcus pneumoniae and Enterococcus faecalis only had low drug resistance rate to vancomycin,tegacycline and linezolid.Escherichia coli,Pseudomonas aeruginosa,Acinetobacter baumannii,Klebsiella pneumoniae and Stenotrophomonas maltophilia were resistant to commonly used antibiotics.Conclusion The detection rate of MDROs is relatively high,and the main types of MDROs are ESBLs and CRAB.The main detected specimens are sputum,and the key departments are ICU-containing departments.The situation of common bacterial resistance is severe.Precision sensing of MDROs should be carried out,and target monitoring and prevention of related factors should be strengthened.
作者
熊自超
黄绍通
郭庚秀
XIONG Zi-chao;HUANG Sao-tong;GUO Geng-xiu(Ganzhou People's Hospital,Ganzhou Jiangxi 341000,China)
出处
《中国消毒学杂志》
CAS
2019年第10期763-766,共4页
Chinese Journal of Disinfection
关键词
多重耐药菌
细菌
耐药性
multidrug-resistant organisms
bacteria
drug resistance
