摘要
牛黄为我国传统名贵中药,有两千多年药用史。牛黄药理作用广泛,研究显示其具有解热、镇痛、抗炎、镇静、降压、利胆、保肝、抗氧化、抗肿瘤、提高免疫力等活性。由于天然牛黄药源紧缺,国家陆续研发批准培植牛黄、人工牛黄、体外培育牛黄替代天然牛黄以供药用。该文采用文献资料法,检索自建国以来国内外公开发表的涉及牛黄及其替代品的药理作用和临床应用的文献,归纳并总结,为今后深入开展牛黄及其替代品基础或临床研究提供参考。
Calculus Bovis（CB） is one of the precious traditional Chinese medicines （TCM） and has been widely used in oriental countries over 2000 years. It possesses a broad spectrum of pharmacological properties such as relieving fever, analgesic, diminishing inflammation, sedation, reducing blood pressure, recovering gallbladder functions, antioxygenation, and anti - tumor and improving immunity, et al. Due to the scarce resource and high price of natural CB, its substitutes, artificially synthesized CB and C. Bovis Sativus （CBS） , also called in vitro cultured C. Bovis, have already been developed and widely used in medicine preparation. By using the literature material method, the current article explored literatures regard to pharmacological activities and clinical application of CB and its substitute, and the compound preparations were also included, from 1949 to 2016 in journals of domestic and foreign. All documents are summarized to provide a valuable reference for further basic or clinical research about CB and its substitute.
出处
《医药导报》
CAS
2017年第4期355-360,共6页
Herald of Medicine
基金
国家自然科学基金资助项目(81573788
81503225)
湖北省卫生厅项目(JX6B49)
关键词
牛黄
中药替代品
药理作用
文献统计
Calculus
Traditional Chinese medicines substitute
Pharmacological activity
Literature statistics
