摘要
目的探讨强化CURB和CURB-65评分对社区获得性肺炎的预后价值。方法采用回顾性研究的方法,选取555例社区获得性肺炎患者,根据患者28 d的转归将其分为治疗有效组(共510例,其中痊愈57例,好转出院453例)和无效组(共45例,其中28 d未好转放弃治疗者30例,死亡15例);两组分别利用强化CURB和CURB-65评分评估患者预后,比较两种评分预测患者病情及预后的敏感性和特异性。结果有效组患者年龄和住院时间以及合并慢性基础疾病均明显低于无效组(P<0.05);无效组强化CURB及CURB-65评分均明显升高,与有效组比较差异有统计学意义(P<0.05);强化CURB评分对社区获得性肺炎的预后分析具有良好的敏感性,而CURB-65评分具有较好的特异性。结论强化CURB和CURB-65评分可以有效判断社区获得性肺炎患者的病情严重程度,用于指导临床治疗。两种评分指标相结合对评估患者的病情及预后具有一定的临床应用价值。
Objective To evaluate the prognostic value of enhanced CURB and CURB-65 score in patients with community acquired pneumonia. Methods A retrospective study was conducted among 555 patients with community-acquired pneumonia recruited. According to the patient's 28 day outcome,they were divided into effective group(n = 510,57 cured and 453 improved) and ineffective group(n = 45,30 did not improve and 15 died). The prognosis of the two groups was evaluated using the enhanced CURB and CURB-65 score,the sensitivity and specificity of the two scoring methods were compared. Results Compared with the ineffective group,the age,length of hospital stay and the prevalence of the complications of chronic diseases were significantly lower than the effective group(P〈0. 05). The score of enhanced CURB and CURB-65 of ineffective group were significantly higher than the effective group(P〈0. 05). The sensitivity of enhanced CURB score was significantly higher than that of CURB-65(P〈0. 05) while its specificity was significantly lower than that of CURB-65(P〈0. 05). Conclusion The CURB and CURB-65 score in community acquired pneumonia can effectively assess the severity of the disease and thus guide the treatment of patients with community acquired pneumonia.
出处
《安徽医科大学学报》
CAS
北大核心
2017年第4期533-536,共4页
Acta Universitatis Medicinalis Anhui
基金
国家临床重点专科建设项目