摘要
目的通过检测血浆NT-pro BNP水平,研究其在慢性心力衰竭(CHF)患者分级中的临床应用。方法选取临床诊断为CHF患者232例为实验组,选取同期门诊健康体检者50例为对照组,采用双抗体夹心免疫法检测所有人空腹血浆NT-pro BNP水平。结果实验组患者血浆NT-pro BNP水平明显高于对照组(P<0.05),且试验组中,随着患者心衰程度不断加重,NT-pro BNP水平也呈增加趋势。对于不同原发病因导致的CHF,NT-pro BNP水平差异无统计学意义(P>0.05)。结论 NT-pro BNP检测成本适中、特异性强、检测时间快,适合各级医院实验室推广普及。此外,NT-pro BNP水平与慢性心衰发生发展呈正相关,应引起临床医生的重视,以阻止或控制CHF患者的病情进一步恶化。
Objective To study the clinical application in patients with chronic heart failure （CHF） throughtesting the plasma NT-proBNP level. Method To select 232 patients with CHF as the experimental group, fiftypatients as the control group. To detect the fasting plasma NT-proBNP level of the all by double antibodysandwich immunoassay. Result The level of NT-proBNP in the experimental group was significantly higherthan that in the control group （P〈0.05）, and the level of NT-proBNP increased with the increase of heart fail-ure. There was no significant difference in the levels of CHF and NT-proBNP between different primary caus-es （P〉0.05）. Conclusion NT-proBNP detection cost is moderate, specificity is strong, detection time is fast,which are suitable for all hospital laboratories to promote. Moreover, NT-proBNP level and chronie heart fail-ure occurred in a positive correlation, which needs clinicians＇ attention to prevent or control the further dete-rioration of CHF patients.
出处
《襄阳职业技术学院学报》
2017年第2期85-87,共3页
Journal of Xiangyang Polytechnic
