摘要
目的探究卵巢癌恶性腹腔积液患者接受热疗联合顺铂对其卵巢癌细胞的毒性增效作用及治疗价值。方法选取2014年1月至2016年1月收治的卵巢癌恶性腹腔积液患者76例,按照随机数字表法分为2组,对照组接受常规顺铂治疗,试验组接受热疗联合顺铂,对比2组卵巢癌恶性腹腔积液患者治疗结果。结果 2组疗效、SKOV3凋亡情况差异有统计学意义(P<0.05)。2组不良反应差异无统计学意义(P>0.05)。结论卵巢癌恶性腹腔积液患者接受热疗联合顺铂进行治疗,对其卵巢细胞具有较强的毒性增效作用,可提高患者的疗效。
Objective To explore the effect of hyperthermia combined with cisplatin on the treatment of malignant peritoneal effusion in patients with ovarian cancer and its value in the treatment of ovarian cancer cells. Methods From January 2014 to January 2016, 76 cases of ovarian cancer patients with malignant ascites were divided into 2 groups. The control group received routine cisplatin treatment and the experimental group received hyperthermia combined with cisplatin. Treatment results of ovarian cancer patients with malignant peritoneal effusion were compared between 2 groups. Results Curative effect and SKOV3 apoptosis of 2 groups was significantly different （P〈0.05）. The difference of adverse reactions between the 2 groups was not significant （P〉0.05）. Conclusion Treatment of hyperthermia combined with cisplatin for malignant peritoneal effusion in patients with ovarian cancer has a strong toxicity and synergistic effect on the ovarian cells, which can improve the efficacy of the treatment.
作者
陈礼双
高炳玉
Chen Lishuang Gao Bingyu(Department of Obstetrics and Gynecology , Family Planning Service Center, Qionghai City, Hainan 571400, China)
出处
《山西医药杂志》
CAS
2017年第5期511-513,共3页
Shanxi Medical Journal
关键词
卵巢肿瘤
腹水
高温
诱发
顺铂
Ovarian neoplasms
Ascites
Hyperthermia, induced
Cisplatin
