摘要
目的:观察补肾化痰法治疗多囊卵巢综合征临床疗效。方法:随机将180例多囊卵巢综合征患者分为对照组和治疗组,对照组给予盐酸二甲双胍(口服,500 mg/次,日3次)及枸橼酸氯米芬胶囊(于月经周期第5天口服,50 mg/次,日1次,连续服用5 d)联合应用治疗,治疗组给予中药补肾化痰汤加减(口服,100 m L/次,日2次)治疗,治疗3个月。分别于治疗前后抽取患者外形周静脉血,观察血清性激素(FSH、LH、E2、T)水平变化;对2组患者排卵、月经周期及妊娠情况进行监测,观察2组患者临床总有效率。结果:血清学检查发现:治疗3个月后,与治疗前比较2组患者血清LH、T水平显著降低(P<0.05,P<0.01),E2水平显著升高(P<0.05,P<0.01);与对照组比较,治疗组患者血清LH、T水平降低(P<0.05),E2水平升高(P<0.05);排卵、月经周期及妊娠情况监测结果表明,与对照组比较,治疗组患者总排卵率、月经周期总恢复率、总妊娠率及临床总有效率明显升高(P<0.05)。结论:补肾化痰法治疗多囊卵巢综合征临床疗效确切,值得进一步推广应用。
Objective： To observe the clinical effect on treating polycystic ovary syndrome with nourishing kidney and resolving phlegm method. Methods ： 180 patients with polycystic ovary syndrome were randomly divided into control group and treatment group, control group was given metformin hydroehloride （ oral, 500 mg/times, 3 times daily ） and Clomifene Citrate Capsules （ oral, 50 mg/times, 1 times a day for 5 days, for fifth consecutive days ） combined treatment. Treatment group was given Chinese medicine Bushen Huatan Decoction （oral, 100 mL/times, two times ）treatment, treatment for 3 months. Peripheral venous blood was extracted before and after treatment, and changes of serum sex hormone （ FSH, LH, E2, T ） levels were observed. The ovulation, menstrual cycle and pregnancy status were monitored in 2 groups, the clinical total effective rate of the 2 groups were observed. Results ： Serological examination revealed： After three months of treatment, the serum levels of LH and T were significantly decreased （P〈0.05, P〈0.01 ）before and after treatment in 2 groups, E2 level was significantly increased （ P〈0.05, P〈0.01 ）. Compared with the control group, the serum levels of LH and T were decreased in the treatment group （ P〈0.05 ）, and the level of E2 was increased （ P〈0.05 ）. Ovulation, menstrual cycle and pregnancy monitoring results show that, compared with the control group, the total ovulation rate, the total recovery rate, the total pregnancy rate and clinical total effective rate of the treatment group were significantly increased （ P〈0.05 ）. Conclusion ： The clinical effect of nourishing kidney and removing phlegm method in the treatment of polycystic ovary syndrome is definite, which is worth to be popularized and applied.
出处
《辽宁中医药大学学报》
CAS
2017年第2期172-174,共3页
Journal of Liaoning University of Traditional Chinese Medicine
关键词
多囊卵巢综合征
补肾化痰
临床研究
polycystic ovary syndrome
nourishing kidney and resolving phlegm
clinical research
