摘要
目的研究喹硫平治疗阿尔兹海默症患者精神行为症状的临床疗效及不良反应。方法以我院120例阿尔兹海默症住院患者为研究对象,采用随机的方式分为常规组与研究组,每组60例,其中研究组给予喹硫平治疗,常规组给予利培酮治疗,进行为期56 d的治疗,以精神病判定量表(BPRS)、症状量表(TESS)、痴呆病理行为判定量表(BEHAVE-AD)对患者的不良反应进行判断。结果研究组改善状况优于常规组。数据对比差异具有统计学意义(P<0.05)。结论喹硫平治疗阿尔兹海默症精神行为障碍疗效显著,且安全性较高,不良反应较少。
Objective To study the clinical efficacy and adverse reactions of quetiapine in the treatment of senile dementia. Methods 120 cases of senile dementia patients were chosen as the research object in our hospital, using randomly divided into routine group and study group, 60 cases in each group, the study group was treated with quetiapine in the treatment group were given risperidone treatment, routine treatment, for a period of 56 days, to determine the adverse reactions of the patients with the psychiatric judgment scale（BPRS）, the symptom scale（TESS）, and the Alzheimer’s pathological behavior rating scale（BEHAVE-AD）. Results The improvement of the study group was better than that of the conventional group. The difference between the two groups was statistically significant（P〈0.05）. Conclusion Quetiapine is effective and safe in the treatment of senile dementia.
出处
《中国继续医学教育》
2017年第1期179-180,共2页
China Continuing Medical Education
