摘要
目的探讨腹腔镜联合药物治疗子宫内膜异位症合并不孕的疗效。方法收集我院子宫内膜异位症的患者,参考美国生育协会R-AFS分期法分为Ⅰ期、Ⅱ期、Ⅲ期及Ⅳ期。随机分为研究组(治疗方案为腹腔镜联合米非司酮)和对照组(治疗方案为腹腔镜),每组各40例。对比(1)两组术前CA125水平及不孕时间。(2)两组子宫内膜异位症的治疗疗效。(3)两组术后痛经复发率、术后随访1年妊娠率。结果(1)两组术前CA125水平及不孕时间结果比较,差异无统计学意义(P>0.05)。(2)研究组和对照组子宫内膜异位症的治疗疗效分别为77.5%、67.5%,两组结果比较,差异具有统计学意义(P<0.05)。(3)研究组和对照组术后痛经发生率、术后随访1年妊娠率对比,差异均具统计学意义(P<0.05)。结论腹腔镜联合药物治疗子宫内膜异位症合并不孕较单纯采取腹腔镜治疗疗效更为肯定,术后痛经发生率低,怀孕率高。
Objective To investigate the effect of laparoscopy combined with drug therapy in the treatment of endometriosis associated infertility. Methods The collection of endometriosis in our hospital, the reference to the American Fertility Society R-AFS stage is divided into I phase, II phase, III phase and IV phase. Which were randomly divided into study group（treatment program for laparoscopic combined with mifepristone） and control group（treatment program for laparoscopic）, 40 cases in each group. Compare（1） two groups of preoperative CA125 level and the duration of infertility.（2） the therapeutic effect of two groups of endometriosis.（3） the incidence rate of postoperative pain and the rate of 1 year follow-up of two groups. Results（1） there was no difference in the level of CA125 and the duration of infertility before and between two groups（P〈0.05）.（2） the study group and the control group, the treatment of endometriosis were 77.5%, 67.5%, the difference was statistically significant（P〈0.05）.（3） there were significant differences in the incidence of postoperative pain and the rate of postoperative follow-up of 1 years between the study group and the control group（P〈0.05）. Conclusion Laparoscopy combined with drug treatment of endometriosis associated infertility is more positive than the simple laparoscopic treatment, the rate of postoperative dysmenorrhea is low, the pregnancy rate is high.
出处
《中国继续医学教育》
2016年第35期108-110,共3页
China Continuing Medical Education
