摘要
目的:对忍冬木层孔菌Phellinus lonicerinus子实体进行提取、分离、结构鉴定。方法:通过正向硅胶,RP-18及凝胶Sephadex LH-20等材料从忍冬木层孔菌乙酸乙酯部位进行分离纯化,通过波谱分析确定了化合物的结构。结果:分离纯化得到10个化合物,它们分别为亚油酸甲酯(1),麦角甾-4,6,8(14),22-四烯-3-酮(2),过氧麦角甾醇(3),麦角甾-5,7,22-三烯-3β-醇(4),对羟基苯乙醇(5),2,5-呋喃二甲醇(6),邻羟基苯乙酸(7),环(亮-缬)二肽(8),麦角甾-7,22-二烯-3β,5α,6β-三醇(9),脑苷脂D(10)。结论:除化合物3,4外其余8个化合物均为首次从该种真菌中分离得到。
Objective： To extract and isolate the chemical constituents from the sporophore of Phellinus lonicerinus and identify their structures. Method： The ethyl acetate extracts of the sporophore of P. lonicerinus were separated and purified by silica gel,RP-18,and Sephadex LH-20 column chromatography. Their structures were identified by spectroscopic analysis. Result： Ten compounds were isolated and identified as methyl linoleate（ 1）,（ 22 E,24R）-ergosta-4,6,8（ 14）,22-tetraen-3-one（ 2）,（ 22 E,24R）-5α,8α-epidiory-ergosta-6,22-dien-3β-ol（ 3）,（ 22 E,24R）-ergosta-5,7,22-trien-3β-ol（ 4）,4-hydroxyphenethyl alcohol（ 5）,furan-2,5-diyldimethanol（ 6）,O-hydroxyphenylacetic acid（ 7）,cyclo-（ Leu-Val）（ 8）,（ 22 E,24R）-ergosta-7,22-dien-3β,5α,6β-triol（ 9）,and cerebroside D（ 10）. Conclusion： All the compounds except compounds 3 and 4were isolated from P. lonicerinus for the first time.
出处
《中国实验方剂学杂志》
CAS
CSCD
北大核心
2016年第24期55-58,共4页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家公益性行业科研专项(201407002)
关键词
忍冬木层孔菌
提取
分离
结构鉴定
Phellinus lonicerinus
isolation
structure
structure identification
