摘要
目的：为雷公藤的鉴别、炮制及热分解产物研究提供参考。方法：采用热重-微商热重（TG-DTG）和差热-微商差热（DTA-DDTA）分析法对3个产地雷公藤及其同属种昆明山海棠、东北雷公藤及其常见伪品藤梨根、野葡萄根进行热谱扫描分析,测定7批药材及其药渣、浸膏样品的热谱,分析雷公藤药材与药渣样品热谱的差谱。结果：7批药材的TG-DTG和DTA-DDTA热谱基本相似,并与本身药渣热谱基本相似。3个产地雷公藤及其同属种昆明山海棠浸膏的DTG曲线均呈（299±3）℃单一主峰,且强度相似,而东北雷公藤及伪品藤梨根和野葡萄根DTG曲线呈多个峰,且（299±3）℃不为主峰。结论：药材热谱不能区分雷公藤及其伪品;浸膏DTG曲线特征可区分雷公藤及其伪品;雷公藤的适宜煨法炮制温度为200-380℃。该研究结果可为雷公藤的鉴别、炮制及热分解产物研究提供一定参考。
OBJECTIVE：To provide reference for the identification,processing,processing technology and research for thermal decomposition products. METHODS：Thermogravimetry- derivative thermogravimetry（TG-DTG）and differential thermal-derivative differential thermal（DTA-DDTA）analysis were conducted to scan thermal spectrum of tripterygium from 3 places and T.hypoglaucum,T. regelii,common counterfeits Actinidia arguta and Vitis quinquangularis,determine 7 medicinal materials,its dregs and extractum,and analyze differential spectrum of T. wilfordii and dregs. RESULTS：The TG-DTG and DTA-DDTA thermal spectrum were not only basically similar to each other but also to their dregs. There was a singlet main characteristics peak at about（299±3）℃ only in the DTG curves of extracts of tripterygium from 3 places and T. hypoglaucum extractum with similar intensity,while T. regelii,counterfeits A. arguta and V. quinquangularis showed multiple peaks,and（299 ± 3）℃ was not the main peak.CONCLUSIONS：The thermal spectrum can not distinguish tripterygium and its counterfeits;extractum DTG curves can do it;suitable processing temperature of tripterygium was 200-380 ℃. The study can provide reference for the identification,processing,processing technology and research for thermal decomposition products.
出处
《中国药房》
CAS
北大核心
2016年第30期4269-4271,共3页
China Pharmacy
基金
江西省自然科学基金资助项目(No.20151BAB205075)
关键词
雷公藤
伪品
热分析
鉴别
炮制
Tripterygium wilfordii
Counterfeit
Thermal analysis
Identification
Processing
