摘要
目的:探讨肠炎清联合谷氨酰胺对肠黏膜损伤患者菌群失调的影响。方法:选取2013年6月—2015年10月武汉市武昌医院收治的肠黏膜损伤患者82例作为研究对象,以随机数字表法分为观察组和对照组各41例。对照组患者口服中药肠炎清,观察组患者在对照组的基础上联合谷氨酰胺治疗。观察2组患者治疗前后肠黏膜情况,比较2组患者菌群失调的情况。结果:治疗后,2组患者肠黏膜评分明显低于治疗前,对照组患者肠黏膜评分显著高于观察组,差异均有统计学意义(P<0.05)。观察组患者治疗菌群失调的总有效率为92.68%(38/41),明显高于对照组的68.29%(28/41),差异有统计学意义(P<0.05)。结论:肠炎清联合谷氨酰胺治疗肠黏膜损伤,能有效减轻肠黏膜损伤程度,修复肠黏膜,改善患者肠道菌群失调。
OBJECTIVE： To probe into the effects of changyanqing combined with glutamine on intestinal flora imbalance in patients with intestinal mucosa injury. METHODS： 82 patients with intestinal mucosa injury admitted into Wuhan Wuchang Hospital from Jun. 2013 to Oct. 2015 were selected to be divided observation group and control group via the random number table,with 41 cases in each. The control group were treated with oral changyanqing,while the observation group additionally received glutamine based on the control group. The intestinal mucosa score of two groups were observed, and the intestinal flora imbalance of two groups were compared. RESULTS： After treatment,the intestinal mucosa score of two groups were lower than that before treatment,and control group was significantly higher than that of observation group,with statistically significant difference（ P〈0. 05）. The total effective rate of the treatment of intestinal flora imbalance in observation group was 92. 68%（ 38 /41）,higher than that of control group [68. 29%（ 28 /41） ], with statistically significant difference（ P〈0. 05）. CONCLUSIONS：Changyanqing combined with glutamine in treatment of intestinal mucosa injury can effectively relieve the intestinal mucosal injury,help to repair the intestinal mucosa and improve the intestinal flora imbalance.
出处
《中国医院用药评价与分析》
2016年第9期1227-1229,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
肠炎清
谷氨酰胺
肠黏膜损伤
菌群失调
临床疗效
Changyanqing
Glutamine
Intestinal mucosa injury
Intestinal flora imbalance
Clinical efficacy
