摘要
目的观察中国超重及肥胖青年大学生血清维生素D的水平,探讨血清维生素D水平与中心动脉收缩压的关系。方法使用ELISA法检测116例超重及肥胖青年大学生[体质指数(BMI)≥24 kg/m2]与149例非超重及肥胖青年大学生(BMI<24 kg/m2)血清维生素D的水平,并分析其与中心动脉收缩压及与肱动脉收缩压、舒张压、平均动脉压的关系。结果超重及肥胖组与对照组年龄、身高、心率的差异无统计学意义。超重及肥胖组体重、右臂围、BMI均高于对照组,差异有统计学意义(P<0.001);超重及肥胖组的中心动脉收缩压、肱动脉收缩压、肱动脉舒张压、肱动脉平均动脉压均高于对照组,差异有统计学意义(P<0.001);中心动脉收缩压与肱动脉收缩压(r=0.914,P<0.001)、肱动脉舒张压(r=0.745,P<0.001)和肱动脉平均动脉压(r=0.823,P<0.001)呈正相关性;超重及肥胖组血清维生素D水平低于对照组,差异有统计学意义(P<0.01),且血清维生素D水平与中心动脉收缩压呈负相关性(r=-0.375,P<0.001)。结论超重及肥胖青年大学生血清维生素D水平低于非超重青年大学生,并且与中心动脉收缩压呈负相关性,预示维生素D可能参与了肥胖及超重青年大学生血压升高的发生发展。
Objective To observe the change of serum vitamin D concentrations in the overweight or obese college students , and to analyze the relationship between serum vitamin D concentrations and central systolic blood pres- sure（CSBP）. Methods Compare the levels of serum vitamin D between 116 overweight or obese college students （BMI ≥24 kg/m2） and 149 normal weight college students （BMI 〈 24 kg/m2）, to analyze the relationship between serum vitamin D and CSBP, SBP,DBP, MAP. Results There was no significant difference in age, height and heart rate between the two groups. The weight, arm circumference and BMI in overweight or obese group were higher than that the in control group, the difference was statistically significant（P 〈 0. 001 ）. Compared with the control group, the CSBP, SBP, DBP and MAP were higher in the overweight or obese group. The difference was statisti- cally significant（P 〈 0. 001 ）, and there was positive correlation between CSBP and SBP（ r = 0. 914, P 〈 0.01 ）, DBP（r = 0. 745 ,P 〈 0. 01 ）, MAP （r = 0. 823, P 〈 0.01 ）. Compared with the control group , the serum vitamin D concentrations were lower in the overweight or obesity group （P 〈 0. 001 ） , and there was negative correlation be- tween vitamin D and CSBP（r = - 0. 377,P 〈 0.01 ）. Conclusion The level of serum vitamin D in overweight or obese college students is lower than the normal weight college students. And it is associated with CSBP,SBP,DBP, MAP which indicate that vitamin D may participate in the development of blood pressure in the obese and over- weight college students.
作者
廖明媛
田建伟
王新宴
许波
余成
徐斌
张亚华
Liao Mingyuan Wang Xinyan et al(Graduate School of Anhui Medical University, Hefei 230032 Dept of Cardiovascular Diseases Dept of Special Clinic Air,Force General Hospital, Beijing 100142)
出处
《安徽医科大学学报》
CAS
北大核心
2016年第10期1525-1528,共4页
Acta Universitatis Medicinalis Anhui
基金
科技基础性工作专项项目(编号:2013FY114000)
关键词
维生素D
中心动脉收缩压
超重
肥胖
vitamin D
central systolic blood pressure
overweight
obese
