摘要
目的:优化超临界CO_2萃取干姜的工艺条件。方法:采用均匀设计法,以姜酚类成分6-姜酚、8-姜酚、10-姜酚的含量和干姜油萃取率的综合评分为指标,考察萃取压力、萃取温度、萃取时间3个因素对萃取效果的影响;同时进行验证试验。结果:优化的萃取工艺为压力25 MPa、温度30℃、时间2 h;验证试验中干姜油的平均萃取率为3.2%,综合评分为1.874 2(RSD=0.65%,n=3);实测值与预测值的相对偏差为0.6%。结论:所得最优萃取工艺条件稳定可行,具有温度低、耗时短等优点。
OBJECTIVE： To optimize the technology of supercritical CO2 extraction from Zingiberis rhizoma. METHODS： With the comprehensive score of the contents of 6-ginger phenol, 8-ginger phenol and 10-ginger phenol and the extraction rate of the oil from Z. rhizoma as the index, uniform design method was adopted to investigate the effects of extraction pressure, extrac- tion temperature and extraction duration on the extraction result; verification tests were conducted. RESULTS： The optimal condi- tions were as follows as the extraction pressure of 25 MPa, extraction temperature of 30 ℃ and extraction duration of 2 h. In the verification tests, the average extraction rate of the oil from Z. rhizoma was 3.2% （n= 3）, and the comprehensive score was 1.874 2 （RSD=0.65%, n=3）, with the relative deviation of 0.6% between the measured value and the predicted value. CONCLUSIONS： The optimal extraction technology is stable and feasible, with the advantages of low temperature, short duration.
出处
《中国药房》
CAS
北大核心
2016年第25期3552-3554,共3页
China Pharmacy
基金
河南省科技攻关计划项目(No.092102310112)
呼吸疾病诊疗与新药研发河南省协同创新中心基金项目(No.20130012)
关键词
干姜
超临界CO2萃取
均匀设计
姜酚类成分
提取率
Zingiberis rhizoma
Supercritical CO2 extraction
Uniform design
Ginger phenolic components
Extraction rate
