摘要
目的分析职业性镉接触人群泌尿、血液、呼吸系统相关指标的变化。方法比较某镍镉电池厂镉接触人群(n=100)与无镉接触对照人群(n=81)尿镉、尿β2-微球蛋白、血红蛋白、红细胞、白细胞、血小板、FEV1/FVC(第1 s用力呼气容积/用力肺活量)的差异。结果该厂工人作业环境中镉浓度超过国家标准。接触组尿镉超标率(25%,25/100)显著高于对照组(2.47%,2/81)(P<0.001),尿镉、β2-微球蛋白水平显著高于对照组(P<0.05),血红蛋白显著低于对照组(P<0.05)。接触组和对照组之间红细胞、白细胞、血小板、FEV1/FVC差异无统计学意义(P>0.05)。结论镍镉电池厂镉接触会使尿镉、β2-微球蛋白值增加,并导致贫血。
Objective To analyze the changes of related indexes of urinary, blood and respiratory systems in the group occupationally exposed to cadmium. Methods The concentrations of urinary cadmium, β2-microglobulin （β2-MG） , hemoglobulin （HB） , red blood cell （RBC） , white blood cell （WBC） , platelet （PLT） and forced expiratory volume in 1 second/forced vital capacity （FEV1/FVC） were compared between the occupationally cadmium-exposed group （n= 100） and the non-cadmium-exposed group （ control group, n = 81 ） in a nickel-cadmium battery factory. Results The concentration of cadmium in the work- place of the factory exceeded the national standard. The exceeding standard rate of urinary cadmium of the occupationally cadmium -exposed group （ 25%, 25/100） was higher than that of the control group （ 2.47%, 2/81 ; P〈0.001 ）. The levels of urinary cadmi- um and β2-MG were significantly higher in the occupationally cadmium-exposed group than in the control group （ P〈0.05 ） , while the level of HBC was significantly lower in the occupationally cadmium-exposed group than in the control group （P〈0.05）. No sta- tistically significant differences were found in the concentrations of RBC, WBC, PLT and FEV/FVC between the two groups （ P〉 0. 05 ）. Conclusions Cadmium exposure in the nickel-cadmium battery factory can induce the increase of urinary cadmium and β2-MG as well as anemia.
出处
《实用预防医学》
CAS
2016年第9期1147-1149,共3页
Practical Preventive Medicine
基金
国家自然科学基金(81273026)
湖南省自然科学基金(12JJ3098)
湖南省卫计委科研基金(B2011-044)
关键词
镉接触
尿镉
Β2-微球蛋白
血红蛋白
呼吸系统
Cadmium exposure
Urinary cadmium
β2- microglobulin
Hemoglobin
Respiratory system
