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中国儿童幽门螺杆菌感染流行病学现状与变迁 被引量:28

Epidemiology and dynamic change of Helicobacter pylori infection in Chinese children
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摘要 发达国家和发展中国家幽门螺杆菌(Hp)感染率存在明显差异,包括中国在内的发展中国家Hp感染率远高于发达国家。Hp感染是中国儿童最常见的慢性细菌性感染之一,既往研究资料显示各地区差异较大。近年来,发展中国家和发达国家的Hp感染率及相关疾病均呈现下降趋势。近期发表的一项中国多中心、前瞻性研究显示,Hp感染在中国无症状儿童中较常见,南北各地区之间总体差异无统计学意义,感染率随着年龄增加而上升,10岁后尤其明显。北京地区近20年来儿童Hp感染呈现下降趋势,提示社会经济状况的改善可能有助于降低儿童Hp感染率。 The occurrence of Helicobacter pylori (H.pylori) infection is significantly higher in developing countries when compared to developed nations. It is one of the most common chronic bacterial infectious in China and significant geograph- ic differences among regions are likely to present. The rates of H.pylori infection and related diseases have been declining yearly in both developed and rapidly developing countries. A prospective, muhicenter study performed recently in China in- dicates that H.pylori infection rate among Chinese asymptomat- ic children increases with age and is high after the age of ten. There is no overall regional difference among different cities. H.pylori infection rate in children has declined in Beijing in re- cent 20 years since 1991, which indicates that improvement in socioeconomic conditions might have helped to reduce the in- fection rate in children.
作者 丁召路
出处 《中国实用儿科杂志》 CSCD 北大核心 2016年第7期497-499,共3页 Chinese Journal of Practical Pediatrics
关键词 幽门螺杆菌 流行病学 变迁 Helicobacter pylori epidemiology dynamic change
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