摘要
胃癌是我国最常见的恶性肿瘤之一.胃癌的发生、发展与机体免疫状态有密切的关系.T淋巴细胞不仅是人体细胞免疫的主要效应细胞,而且是重要的免疫调节细胞,维持机体正常免疫功能,在杀伤肿瘤细胞、控制肿瘤生长中起重要作用.当外周T淋巴细胞亚群在数量和功能发生异常时,可导致免疫系统紊乱并发生一系列的病理变化,进而可导致肿瘤的发生、发展.T淋巴细胞亚群在恶性肿瘤发病机制中的作用日益受到人们重视.本文就胃癌与T淋巴细胞亚群关系的研究进展进行综述.
Gastric cancer is one of the most common malignant tumors in China.The occurrence and development of gastric cancer are closely related to the body＇s immune status.T-lymphocytes are not only the main effector cells of the body＇s immune system,but also important immunoregulatory cells,playing important roles in maintaining normal immune function,killing tumor cells and inhibiting tumor growth.When the number or function of peripheral T-lymphocyte subsets is abnormally altered,disorders of the body＇s immune system and some pathological changes may occur,which can lead to the occurrence and development of tumors.T-lymphocyte subsets have been gradually recognized to play an important role in the pathogenesis of malignant tumors.The purpose of this review is to summarize the relationship between gastric cancer and T-lymphocyte subsets.
出处
《世界华人消化杂志》
CAS
2016年第15期2331-2335,共5页
World Chinese Journal of Digestology
