摘要
目的总结婴幼儿孢子丝菌病的临床特征、病理特点和治疗效果，提高临床医生对本病的认识，减少误诊。方法对7年间经真菌培养确诊的20例婴幼儿孢子丝菌病进行回顾分析，并与文献报告相比较。结果本组病例发病部位均为面部。皮损表现为炎性肉芽肿或结痂渗出性斑块。其中固定型15例（75．00％），淋巴管型5例（25．00％）。主要病理类型为非特异性炎性肉芽肿改变。20例患儿应用特比萘芬7．5～10mg／（kg·d），连续服用3个月后，均治愈，且无不良反应。结论婴幼儿孢子丝菌病并非少见，口服特比萘芬7．5～10mg／（kg·d）安全有效，耐受性好。
Objective To summarize the clinical features,pathology and therapeutic efficacy of cutaneous sporotrichosis in infants and to highlight its recognition in order to reduce misdiagnosis. Methods Twenty cases of infants with Sporotrichosis which were confirmed by fungal culture during 7 years were retrospectively analyzed and were compared with review in the literature. Results All patients were involved in facial lesions. Fixed cu- taneous and lymphocutaneous sporotrichosis were seen in 15 （75.00%） and 5 （25.00%） patients, respec- tively. Twenty patients showed inflammatory granuloma or plaque with scab and exudation. The main feature of pathology was nonspecific inflammatory granuloma. All the patients were treated with 7. 5 - 10mg,/（kg· d） terbinafine （Lamisil） ,and all of them were cured after 3 months of treatment without adverse effects. Con. elusion Sporotriehosis is not a rare disease in infants. The daily dose of terbinafine for infants is 7.5 - 10mg/（ kg· d） ,which is effective and safe for infants, and have well toleracne.
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2016年第6期586-588,606,共4页
The Chinese Journal of Dermatovenereology
基金
北京市医院管理局临床医学发展专项经费(ZYLX201601)
