摘要
孢子丝菌病是由申克孢子丝菌复合体感染皮肤、皮下组织、黏膜和局部淋巴系统所引起的慢性感染性疾病。临床表现多样,皮损主要表现为慢性炎症性肉芽肿损害。自1898年报道第一例孢子丝菌病后,对孢子丝菌病的认识越来越深刻,包括孢子丝菌病原体的变迁及其诊断和治疗方法的改进。病原体从申克孢子丝菌单一菌种到目前孢子丝菌复合体的认识。诊断方法包括真菌学检查、组织病理检查、孢子丝菌素以及分子生物学诊断;治疗方法包括碘化钾、伊曲康唑、特比萘芬、两性霉素B口服以及物理和手术疗法等。
Sporotrichosis is a chronic cutaneous infection caused by Sporothrix schenckii complex. The clinical manifestations are diverse,that mainly are expressed as chronic inflammatory granuloma damage. Since sporotrichosis was firstly reported in 1898,from the acknowledgement of only one specice of Sporothrix schenckii to Sporothrix schenckii complex（ six specices）,and with the development of diagnosis and treatment,there is a more profound understanding of sporotrichosis. The methods of diagnosis include fungal examination,histopathological examination,sporemycin and molecular biological diagnosis. The methods of treatment include oral taking potassium iodide,itraconazole,terbinafine,amphotericin B,physical and surgical therapy.
出处
《皮肤科学通报》
2017年第5期556-564,共9页
Dermatology Bulletin
关键词
孢子丝菌病
临床表现
诊断
治疗
变迁
Sporotrichosis
Clinical manifestation
Diagnosis
Treatment
Changes
