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某些抗生素类生长促进剂和胆盐水解酶抑制剂作用机制 被引量:1

Mechanism of Some Antibiotic Growth Promoters and Bile Salt Hydrolase Inhibitors
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摘要 某些抗生素类生长促进剂(AGP)如四环素和洛克沙砷的促生长作用与降低胆盐水解酶(BSH)活性有关,BSH是一种由肠道微生物产生的酶,它对宿主脂肪的消化和利用有负面影响。有研究表明,使用某些抗生素能显著降低乳酸杆菌的数量,而肠道内大部分的BSH是由乳酸杆菌产生的。因此在日粮中添加BSH抑制剂可能会促进宿主脂肪代谢以及能量吸收,从而有助于改善畜禽的生产性能。 The growth -promoting effect of some antibiotic growth promoters and roxarsone was closely (AGP) including tetracycline related with decreased bile salt hydrolase (BSH) activity, which is produced by intestinal microhiota. BSH has an adverse impact on fat digestion and utilization of host. Researches demonstrated that some AGP could decrease population of Lactohacillus spp., which prodnced most BSH in the intestine. Therefore, addition of BSH inhibitor could promote host lipid metabolism and ahsorption, which wouht contribute to enhancingenergy animal growth performance.
作者 王政 张大伟
出处 《中国畜牧杂志》 CAS 北大核心 2016年第10期38-42,共5页 Chinese Journal of Animal Science
关键词 AGP BSH BSH抑制剂 AGP BSH BSH inhibitor
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