摘要
目的:探讨精索静脉高位结扎术联合抗氧化剂治疗精索静脉曲张不育症精子质量的影响。方法:对20例精索静脉曲张不育症患者应用精索静脉高位结扎术联合抗氧化进行治疗,术前和术后6个月分别检测精液常规及总抗氧化能力(TAC),并选择12例健康男性为对照组,观察术前精液常规及TAC与对照组的差异。结果:精索静脉曲张不育症患者在精液量,精子密度,精子活力和TAC水平均明显低于健康组,差异均有显著的统计学意义(P<0.01);手术后精索静脉曲张不育Ⅱ°组和Ⅲ°组患者精液量、精子密度和精子活力及TAC水平明显提高,与手术前比较差异有明显的统计学意义(P<0.05),术前少弱畸形精子综合征TAC水平明显低于少精子症和少弱精子症患者,差异有明显的统计学意义(P<0.05),三组患者术后TAC水平明显升高,与治疗前比较差异具有明显的统计学意义(P<0.05)。结论:氧化应激可能与精索静脉曲张发生不育症的发生密切相关,精索静脉高位结扎术联合抗氧化剂能明显提高精索静脉曲张不育症精子质量。
Objectives： To observe the efficacy of high ligation of spermatic vein combined with antioxidants on sperm in infertility patients with varicocele. Methods： 20 infertility patients with varicocele were treated with high ligation of spermatic vein combined with antioxidants. Sperm routine and total antioxidant capacity（ TAC） levels before treatment and 6 months after treatment were measured. Results： Semen volume,sperm density,sperm activity and TAC levels of infertility patients were significantly lower than these in the healthy group,with significant difference（ P〈0. 01）. Semen volume,sperm concentration and sperm motility,and TAC levels of II ° and III °Varicocele surgery infertile patients were significantly increased,with statistically significant difference（ P〈0. 05）.Before operation,TAC level of patients with teratospermia was significantly lower than that in oligospermia and asthenospermia patients,with statistically significant difference（ P〈0. 05）. TAC levels were significantly improved after operation in the three groups,with statistically significant difference compared with that before treatment（ P〈0. 05）. Conclusion： Oxidative stress may be in a close relationship with infertility patients with varicocele. Operation combined with antioxidants can significantly improve the sperm quality in infertile men with varicocele.
出处
《中国性科学》
2016年第5期110-112,共3页
Chinese Journal of Human Sexuality
