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正交试验优选银翘散高压煎药机最佳煎煮工艺 被引量:5

Optimization of decoction process for Yinqiao Powder with high pressure Chinese materia medica extructor by orthogonal experiments
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摘要 目的:研究银翘散高压煎药机最佳煎煮工艺。方法:本试验选取绿原酸、芦丁、橙皮苷、牛蒡苷、连翘苷、合煎液中浸出物与相对密度为指标,采用单因素考察和正交试验相结合的方法,选择浸泡时间、加水量、煎煮时间3个因素,每个因素选取3个水平进行正交试验。结果:加水量对检测指标具有显著性影响。结论:银翘散高压煎药机最佳煎煮工艺为A3B3C2组合,即将银翘散组方饮片浸泡45min,加14倍水,煎煮20min,煎煮1次。 Objective: To investigate the optimal high pressure Chinese materia medica(CMM) decoction process for Yinqiao Powder by orthogonal experiments. Methods: Single-factor test combined with orthogonal test were used in this experiment, chlorogenic acid, rutoside, arctiin, phillyrin, hesperidin, extraction of solution and relative density were selected as testing indexes, and soaking time, water amount and boiling time were selected as three influencing factors, orthogonal test was carried out with three levels of each factor. Results: Water amount showed significant influence on the testing indexes. Conclusion: The optimal high pressure CMM extractor decoction process for Yinqiao Powder by orthogonal experiments was the combination of A3B3C2, as soaking the decoction pieces of Yinqiao Powder for 45 mins with 14 times the amount of water, then decocting the solution for 20 mins.
出处 《中华中医药杂志》 CAS CSCD 北大核心 2017年第7期3144-3149,共6页 China Journal of Traditional Chinese Medicine and Pharmacy
基金 国家自然科学基金项目(No.81503216) 江苏省"六大人才高峰"第九批项目(No.WS-029) 全国首批中药特色技术传承人才项目 南京市科技发展计划国际联合研发项目(No.20160508)~~
关键词 正交试验 银翘散 煎煮工艺 绿原酸 芦丁 牛蒡苷 连翘苷 橙皮苷 Orthogonal experiments Yinqiao Powder Decoction process Chlorogenic acid Rutoside Arctiin Phillyrin Hesperidin
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