摘要
目的探讨平均血小板体积(mean platelet volume,MPV)和血脂水平变化与突发性耳聋(sudden deafness,SD)的关系。方法收集2014年1月至2015年12月我院115例SD患者和116例健康体检者,将SD患者分为中度耳聋、中重度耳聋、重度耳聋三组,检测所有受试者的血脂和MPV水平,对检测结果进行统计学分析。结果 SD患者组的MPV、总胆固醇、低密度脂蛋白胆固醇、脂蛋白a水平均显著高于对照组,高密度脂蛋白胆固醇水平显著低于对照组,差异均有统计学意义(P均<0.01),甘油三酯水平在两组间差异无统计学意义(P>0.05);不同程度耳聋患者的MPV和血脂各参数之间差异均无统计学意义(P均>0.05)。结论 MPV和血脂水平与SD发病密切相关,同时检测MPV和血脂水平可以预测SD的患病风险,为SD的临床发病机理研究提供依据。
Objective To investigate the mean platelet volume（MPV） and blood lipid level change and the relationship with sudden deafness（SD）.Methods 115 cases SD patients and 116 cases of healthy people in our hospital from January 2014 to December 2015 were collected in the study.SD patients were divided into mild deafness group,moderately severe deafness group and severe deafness group.The blood lipid and MPV levels of all the subjects were detected,and the results were analyzed statistically.Results The levels of MPV,total cholesterol,low-density lipoprotein cholesterol,lipoprotein（a） in patients with SD were significantly higher than that of control group,high-density lipoprotein cholesterol was significantly lower than that of control group,and the differences all had statistical significance（Pall〈 0.01）.There was no statistical significance in the difference of triglyceride level between the two groups（P 〉0.05）.There were no statistical significance in the differences of MPV and blood lipid parameters levels among three different level SD groups（Pall 〉0.05）.Conclusion MPV and lipid levels are closely associated with the onset of SD,which providing the basis for the clinical pathogenesis of SD.MPV and lipid levels detection can predict the risk of SD.
出处
《实用检验医师杂志》
2016年第1期26-28,共3页
Chinese Journal of Clinical Pathologist
关键词
平均血小板体积
血脂
突发性耳聋
关系
Mean platelet volume
Blood lipid
Sudden deafness
Relationship
