摘要
目的探讨DCE-MRI定量和半定量参数对时间-信号强度曲线表现为平台型前列腺癌灶和前列腺增生的鉴别诊断价值。方法回顾性分析48例时间-信号强度曲线呈平台型的前列腺疾病患者(前列腺癌26例,前列腺增生22例)DCE-MRI定量和半定量参数,包括容积转移常数(K^(trans))、转移速率常数(K_(ep))、血管外细胞外间隙容积分数(V_e),血容量(BV)、血流量(BF)、达峰时间(TTP)。并运用SPSS进行统计学分析。结果在DCE-MRI时间-信号强度曲线为平台型的前列腺癌灶组和前列腺增生组Ktrans、Kep、BF值分别为(2.33±0.93)min^(-1)和(1.21±0.71)min^(-1)、(3.46±1.41)min^(-1)和(1.81±0.85)min^(-1)、(182.63±74.79)ml·g^(-1)·min^(-1)和(140.88±50.73)ml·g^(-1)·min^(-1),组间差异均有统计学意义(P<0.05)。结论 K^(trans)、K_(ep)、BF值在前列腺癌灶组和前列腺增生组间差异存在统计学意义,DCE-MRI定量和半定量参数对平台型时间-信号强度曲线的前列腺癌灶和前列腺增生间的鉴别具有一定的价值。
Objective To assess the quantitative and semi-quantitative parameters of DCE-MRI for the differentiation of prostate lesions with platform type of time-signal intensity curve. Methods Forty eight patients with platform type of time-signal intensity curve in prostate diseases underwent DCE-MRI at 3. 0 T MRI,which includes 26 patients with prostate cancer and 22 with prostate hyperplasia. Ktrans,Kep,Ve,BV,BF and TTP parameters were compared between prostate cancer and benign nodules. All patients received conventional MRI and DCE-MRI scan. Results The average values of Ktrans,Kep,BF for prostate cancer and begin lesions were( 2. 33 ± 0. 93) min-1vs( 1. 21 ± 0. 71) min-1,( 3. 46 ± 1. 41) min-1vs( 1. 81 ± 0. 85) min-1,( 182. 63 ± 74. 79) ml·g-1·min-1vs( 140. 88 ± 50. 73) ml·g-1·min-1,respectively. There was statistically significant difference in Ktrans,Kep,BF between prostate cancer and begin nodules( P 〈 0. 05). Conclusion Quantitative and semiquantitative assessments of Ktrans,Kepand BF in DCE-MRI is useful in the differentiation of prostate cancer and begin nodules.
出处
《临床放射学杂志》
CSCD
北大核心
2016年第4期589-592,共4页
Journal of Clinical Radiology