摘要
目的:观察左炔诺孕酮宫内缓释系统(曼月乐)对无排卵性子宫出血患者的影响。方法:67例无排卵性子宫出血患者应用曼月乐,记录治疗前后患者月经量、子宫内膜厚度、血红蛋白、子宫内膜的内皮素(ET)含量和并发症变化情况。结果:治疗12个月后,患者月经量和子宫内膜厚度明显下降,血红蛋白明显升高(P<0.01)。子宫异常出血比例明显下降,子宫内膜ET含量明显降低(P<0.05),且随着治疗时间的延长子宫内膜的ET含量降低更明显。并发症率由治疗前的50.74%降低到7.46%。结论:应用曼月乐治疗无排卵性子宫出血患者效果显著。
Objective： To analyze the effect of levonorgestrel releasing intrauterine system（ Mirena） on endometrium in the patients with anovulatory uterine bleeding. Methods： Totally 67 cases of anovulatory uterine hemorrhage were treated with Mirena. The menstrual blood volume,uterine endometrial thickness,hemoglobin,endometrial ET content and complications were recorded before and after the treatment. Results： After the 12-month treatment,the menstrual blood volume and endometrial thickness were significantly decreased,and hemoglobin was significantly increased（ P〈0.01）. The percentage of abnormal uterine bleeding was significantly decreased,the ET content in endometrium was significantly decreased（ P 〈0.05）,and the ET content was decreased significantly with the prolongation of the treatment time. The complication rate was reduced from 50.74% to 7.46%. Conclusion： Mirena is notably effective in the treatment of the patients with anovulatory uterine bleeding.
出处
《中国药师》
CAS
2016年第4期734-736,共3页
China Pharmacist
关键词
无排卵性子宫出血
左炔诺孕酮宫内缓释系统
子宫内膜
Anovulatory uterine bleeding
Levonorgestrel releasing intrauterine system
Endometrial
