摘要
目的:分析哮喘急性发作的临床特点,探讨采用不同剂量麻黄的小青龙汤治疗哮喘急性发作的治疗效果,为临床提供参考。方法:选取56例哮喘急性发作的患者,随机分为治疗组A和治疗组B,两组均给予常规的治疗,在此基础上治疗组A使用低剂量麻黄(10g)的小青龙汤治疗,治疗组B使用高剂量麻黄(30g)的小青龙汤治疗,两组患者均给予治疗2周,对比分析治疗前后两组临床效果、不良反应发生率及主要生理指标变化。结果:治疗组A的临床总有效率为71.4%,治疗组B为92.9%,治疗组B较治疗组A有显著性差异(P<0.05);治疗组A的FEV、FEV1、FEV/FEV1分别为(3.03±0.41)L、(2.03±0.48)L、(82.23±9.58)%,治疗组B的FEV、FEV1、FEV/FEV1分别为(3.46±0.52)L、(2.38±0.58)L、(94.61±10.23)%,治疗组B的肺功能指标较治疗组A有显著性差异(P<0.05);两组均未出现严重的不良反应。结论:含有高剂量麻黄的小青龙汤用于治疗哮喘急性发作,可明显改善患者的肺功能指标,临床治疗效果较好,且安全、有效、可靠,对临床治疗哮喘急性发作有一定的指导意义。
Objective： This paper was to investigate the clinical features of acute asthma attacks and to explore the use of Xiaoqinglong Decoction containing different doses of Ephedra in treatment of acute asthma in order to provide the reference for clinical use.Methods： A total of 56 patients with acute asthma were selected and randomly divided into group A and group B.Two groups were given the conventional treatment.Group A was given Xiaoqinglong Decoction containing low-dose Ephedra（ 10 g） for treatment and group B high-dose Ephedra（ 30 g）.Patients were treated for 2 weeks.The clinical effects after treatment,the incidence of adverse events and major physiological changes in both groups were analyzed.Results： The clinical total effective rate of group A was 71.4% while in group B was 92.9% and there was significant difference in two groups（ P〈0.05）.FEV,FEV1 and FEV / FEV1 in group A respectively were（ 3.03 ± 0.41）L,（ 2.03 ± 0.48） L,（ 82.23 ± 9.58） % while in group B respectively（ 3.46 ± 0.52） L,（ 2.38 ± 0.58） L,（ 94.61 ±10.23） %.Compared with the group A,group B had statistically significant difference on lung function（ P〈0.05）.There were no serious adverse reactions in both groups.Conclusion： The results show that Xiaoqinglong Decoction containing high dose of Ephedra for the treatment of acute asthma attacks can significantly improve the lung function.It is effective,safe and reliable for the clinical treatment of acute asthma.It has some significance for the treatment of acute asthma.
出处
《中华中医药学刊》
CAS
北大核心
2016年第4期949-951,共3页
Chinese Archives of Traditional Chinese Medicine
基金
浙江省医药卫生科学研究基金项目(2012A050)
关键词
麻黄
小青龙汤
哮喘急性发作
Ephedra
Xiaoqinglong Decoction
acute asthma attacks
