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2012年-2013年深圳市罗湖区腹泻患者沙门菌流行特征及耐药情况分析 被引量:13

Analysis of epidemiological characteristics and drug resistance of Salmonella isolated from patients with diarrhea in Luohu district of Shenzhen during 2012-2013
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摘要 目的分析2012年-2013年本辖区腹泻患者中沙门菌的感染情况及耐药特征,为防治沙门菌感染和临床治疗提供依据。方法采用GB 4789.4—2010沙门菌检测方法,对从腹泻患者中分离的49株沙门菌进行分离鉴定,阳性菌株用全自动细菌鉴定仪做生化鉴定及药敏分析。结果沙门菌感染主要以幼年组(0岁~5岁)儿童为主,分离高峰集中在春季、夏季;鼠伤寒沙门菌的分离率最高,菌株对青霉素类及磺胺类药物耐药率较高,存在多重耐药菌株。结论鼠伤寒沙门菌是本辖区感染性腹泻的优势菌型,感染患者的年龄呈现低龄化,沙门菌耐药率呈逐年升高趋势,菌株多重耐药形势严峻。 Objective To analyze the infection and drug resistance of Salmonella strains isolated from patients with diarrhea in Luohu district during 2012- 2013,so as to provide references for the prevention and clinical treatment of Salmonella infection.Methods 49 strains isolated from diarrhea patients were separated and identified by GB /4789. 4—2010 Salmonella test methods,and the positive strains were conducted for biochemical tests and antibiotic resistance analysis by automated microbiology analyzer. Results The youth group( from year 0 to 5) was the main crowd of Salmonella infection. Salmonella strains were isolated mainly in spring and summer; Salmonella typhimurium was with the highest isolation rate,which showed severe resistance to penicillins and sulfamethoxazole,and multiple drug- resistant stains were detected during the research. Conclusion Salmonella typhimurium was the prevalent serotype causing diarrhea in Luohu district,showing a tendency of younger and severe multi- drug resistance. The drug resistant incidence of Salmonella increased year by year.
出处 《中国卫生检验杂志》 CAS 2016年第3期447-449,共3页 Chinese Journal of Health Laboratory Technology
基金 深圳市罗湖区软科学研究计划项目(2012043)
关键词 沙门菌 菌型分布 耐药 Salmonella Serotype distribution Antibiotic resistance
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  • 1纪金玲,廖华芳,崔恩博,鲍春梅,陈素明,曲芬,郭桐生.儿童腹泻病原菌1004株构成及药敏试验结果分析[J].中华临床医师杂志(电子版),2012,6(21):6892-6894. 被引量:13
  • 2谢一俊,郑国櫆,陈建辉,李海丹,罗朝晨,陈亢川.福建省1975—2003年沙门菌监测结果分析[J].海峡预防医学杂志,2004,10(6):7-10. 被引量:19
  • 3Garaizar J, Lopez-Molina N, I,aconcha I, et al. Suitability of PCRfingerprinting, infrequent-restriction-site PCR, and pulsed-field gel electrophoresis, combined with computerized gel analysis, in libra~ typing of Sahnonella enterica serovar enteritidis. Appl Environ Microbio1,2000,66(12) : 5273-5281. 被引量:1
  • 4Ribot EM, Fair MA, Gautom R, et al. Standardization of pulsed- field gel clectrophoresis protocols for the subtyping of Escherichiacoli O157:H7, Salmonella, and Shigella for PulseNet. Foodborne Pathog Dis, 2006,3( 1 ) : 59457. 被引量:1
  • 5Hopkins KL, Kirchner M, Guerra B, et al. Multiresistant Salmonella enterica serovar 4, [ 5 ], 12: i:- in Europe: a new pandemic strain? Euro Surveil1,2010,15(22 ) : 19580. 被引量:1
  • 6Pornruangwong S, Sriyapai T, Pulsrikarn C, et al. Theepidemiological relationship between Sahnonella enterica serovar typhimurium and Sahnonella enterica serovar 4, [5 ], 12: i:- isolates from humans and swine in Thailand. Southeast Asian J Trop Med Public Health ,2008,39 (2) :288-296. 被引量:1
  • 7Hur J, Choi YY, Park JH, et al. Antimierobial resistance, virulence-associated genes, and pulsed-field gel eleetrophoresis profiles of Salmonella enteriea subsp, enteriea sernvar Typhimuriam isolated from piglets with diarrhea in Korea. Can J Vet 1Res,2011, 75( 1 ) :49-56. 被引量:1
  • 8Hoelzer K, Soyer Y, Rodriguez-Rivera LD, et al. The prevalence of multidrug resistance is higher among bovine than human Sahnonella enterica serotype Newport, Typhimurium, and 4,5, 12:i:-isolates in the United States but diffet~ by serotype and geographic region. Appl Environ Microbiol, 2010, 76 ( 17 ) : 5947-5959. 被引量:1
  • 9Switt AI, Soyer Y, Warnick LD, et al. Emergence, distribution, and molecular and phenotypic characteristics of Sahnonella enterica serotype 4, 5, 12: i:-. Foodborne Pathog Dis, 2009, 6 ( 4 ) : 407-415. 被引量:1
  • 10United States Department of Agriculture Report to Congress 1998 FoodNet: An Active Surveillance System for Bacterial Foodborne Diseases in the United States [EB/OL]. (2008-6-2). [-2012 06- 10]. http://www, fsis usda. gov/ophs/rpcong98/rpcong98, htm. 被引量:1

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