摘要
目的分析2012年-2013年本辖区腹泻患者中沙门菌的感染情况及耐药特征,为防治沙门菌感染和临床治疗提供依据。方法采用GB 4789.4—2010沙门菌检测方法,对从腹泻患者中分离的49株沙门菌进行分离鉴定,阳性菌株用全自动细菌鉴定仪做生化鉴定及药敏分析。结果沙门菌感染主要以幼年组(0岁~5岁)儿童为主,分离高峰集中在春季、夏季;鼠伤寒沙门菌的分离率最高,菌株对青霉素类及磺胺类药物耐药率较高,存在多重耐药菌株。结论鼠伤寒沙门菌是本辖区感染性腹泻的优势菌型,感染患者的年龄呈现低龄化,沙门菌耐药率呈逐年升高趋势,菌株多重耐药形势严峻。
Objective To analyze the infection and drug resistance of Salmonella strains isolated from patients with diarrhea in Luohu district during 2012- 2013,so as to provide references for the prevention and clinical treatment of Salmonella infection.Methods 49 strains isolated from diarrhea patients were separated and identified by GB /4789. 4—2010 Salmonella test methods,and the positive strains were conducted for biochemical tests and antibiotic resistance analysis by automated microbiology analyzer. Results The youth group( from year 0 to 5) was the main crowd of Salmonella infection. Salmonella strains were isolated mainly in spring and summer; Salmonella typhimurium was with the highest isolation rate,which showed severe resistance to penicillins and sulfamethoxazole,and multiple drug- resistant stains were detected during the research. Conclusion Salmonella typhimurium was the prevalent serotype causing diarrhea in Luohu district,showing a tendency of younger and severe multi- drug resistance. The drug resistant incidence of Salmonella increased year by year.
出处
《中国卫生检验杂志》
CAS
2016年第3期447-449,共3页
Chinese Journal of Health Laboratory Technology
基金
深圳市罗湖区软科学研究计划项目(2012043)
关键词
沙门菌
菌型分布
耐药
Salmonella
Serotype distribution
Antibiotic resistance