摘要
精准医学是以个体化医疗为基础、随着基因组测序技术快速进步以及生物信息与大数据科学的交叉应用而发展起来的新型医学概念与医疗模式。精准医学通过更深刻地剖析胃癌的疾病特征、病因机制等核心问题为提高胃癌的诊断和治疗提供更多的便利。肿瘤临床数据库是推动精准医学发展的重要保障，因此，必须重视数据库的建设和管理。中山大学肿瘤防治中心胃癌临床数据库由病例数据库、血标本库、组织库以及影像资料库组成，为保证数据库的质量，其设计和管理需要遵循严格的标准化操作（即SOP）模式。在医疗大数据年代，数据共享是提高医学研究水平的重要途径，临床数据库的建设和管理也必须围绕这个宗旨进行不断的强化和创新。
Precision medicine is a new medical concept and medical model, which is based on personalized medicine, rapid progress of genome sequencing technology and cross application of biological information and big data science. Precision medicine improves the diagnosis and treatment of gastric cancer to provide more convenience through more profound analyses of characteristics, pathogenesis and other core issues in gastric cancer. Cancer clinical database is important to promote the development of precision medicine. Therefore, it is necessary to pay close attention to the construction and management of the database. The clinical database of Sun Yat-sen University Cancer Center is composed of medical record database, blood specimen bank, tissue bank and medical imaging database. In order to ensure the good quality of the database, the design and management of the database should follow the strict standard operation procedure （SOP）model. Data sharing is an important way to improve medical research in the era of medical big data. The construction and management of clinical database must also be strengthened and innovated.
出处
《中华胃肠外科杂志》
CAS
CSCD
北大核心
2016年第2期132-137,共6页
Chinese Journal of Gastrointestinal Surgery
基金
基金项目：国家自然科学基金（81372474）
关键词
胃肿瘤
精准医学
数据库
管理
Stomach neoplasms
Precision medicine
Database
Management
