摘要
[目的]观察四物汤联合西药治疗痰瘀互结型稳定型心绞痛疗效。[方法]使用随机平行对照方法,将72例住院及门诊患者按病志号抽签法简单随机分为两组。对照组36例拜阿司匹灵0.1g/次,2次/d;美托洛尔,12.5mg/次,2次/d;硝酸异山梨酯,5mg/次,3次/d;硝酸甘油,0.5mg/次,急性发作时舌下含服。治疗组36例四物汤(熟地黄、赤芍、川芎各10g,当归、桃仁、红花各15g,党参、枳壳、延胡索各12g,甘草10g,瓜蒌15g,半夏12g,薤白10g),1剂/d,水煎400m L,早晚口服,200m L/次。西药治疗同对照组。连续治疗28d为1疗程。观测临床症状、中医症候积分、不良反应。连续治疗2疗程,判定疗效。[结果]临床疗效:治疗组显效27例,有效7例,无效2例,总有效率94.44%。对照组显效19例,有效9例,无效8例,总有效率77.78%。心电图疗效:治疗组显效19例,有效10例,无效7例,总有效率80.56%。对照组显效12例,有效8例,无效16例,总有效率55.56%。治疗组疗效优于对照组(P<0.05)。症状积分两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]四物汤联合西药治疗痰瘀互结型冠心病稳定型心绞痛疗效满意,无严重不良反应,值得推广。
[Objective]To observe Siwutang treatment phlegm type with stable angina pectoris.[Methods]Randomized parallel controlled method,72 cases of inpatient and outpatient disease Zhi No.lottery law by simple random into two groups.The control group of 36 patients with aspirin,0.1g/times,2 times/d;metoprolol,12.5mg/times,2 times/d;isosorbide dinitrate,5mg/time,3 times/d;nitroglycerin,0.5mg/times,acute onset sublingual.The treatment group 36 cases Siwutang（Shudihuang,Chishao,Chuanxiong 10 g,Danggui,Taoren,Honghua each 15 g,Dangshen,Zhike,Yanhusuo each 12 g,Gancao 10 g,Gualou 15 g,Banxia 12 g,Xiebai 10g）,1/d,decoction 400 m L,sooner or later,oral,200 m L/times.Western medicine with the control group.28 d for a course of continuous treatment.Observation of clinical symptoms,symptom scores,adverse reactions.2 courses of continuous treatment,to determine efficacy.[Results]Clinical efficacy： treatment group,27 cases markedly effective in 7 cases,2 cases,the total efficiency of 94.44%.The control group 19 cases markedly effective in 9 cases,8 cases,the total efficiency 77.78%.ECG efficacy： treatment group 19 cases,10 cases,7 cases,the total efficiency of 80.56%.The control group 12 cases markedly effective in 8 cases,16 cases,the total efficiency of 55.56%.Treatment group than the control group（P〈0.05）.Symptom scores improved in both groups（P〈0.01）,treatment group was better than that in the control group（P〈0.05）.[Conclusion]Siwutang treatment phlegm type stable angina results were satisfactory,no serious adverse reactions,is worth promoting.
出处
《实用中医内科杂志》
2015年第11期122-124,共3页
Journal of Practical Traditional Chinese Internal Medicine
