摘要
目的评价低渗透压口服补液盐（ORS）溶液联合思密达治疗小儿腹泻病的疗效。方法随机选取2012年1月-2014年1月于肠道门诊就诊的腹泻病患儿153例为研究对象，随机分成三组，其中予低渗ORS溶液治疗的患Jbso例，为A组；普通ORS溶液联合思密达治疗的患J1,53例，为B组；低渗ORS联合思密达治疗的患儿50例，为C组，观察并比较治疗第3天及第5天的大便性状、次数及呕吐情况等，并比较三种治疗方案的72h显效率。结果三组患儿在年龄、性别、临床症状（如呕吐、腹泻次数、脱水程度及精神状态等）方面差异无统计学意义（P〉0．05）。第3天，C组在大便次数和性状以及呕吐次数方面明显优于A组和B组（P〈0．05），A组和B组在大便次数、性状和呕吐次数上差异无统计学意义（P〉0．05）；继续随访，第5天三组病情均好转，在大便次数、性状及呕吐次数方面差异无统计学意义（P〉0．05），但72h显效率C组优于A组和B组，差异具有统计学意义（P〈0．05）。结论低渗透压ORS溶液联合思密达治疗时能缓解呕吐症状，改善腹泻患儿大便次数及性状，72h显效率高。
Objective To evaluate the effect of low osmolarity ORS and smecta in children with diarrhea. Methods 153 diarrhea patients were recruited in this research, who were randomly selected from diarrhea outpatient clinics in our department. They were divided into 3 groups： Group A of 50 cases were treated with low osmolarity ORS, Group B of 53 cases were treated with ORS 11 and smecta, Group C of 50 cases were treated with low osmolarity ORS and smecta, then character and frequency of the stools, vomiting times were recorded on the 3rd and 5th day after treatment, and significant efficiency in 72 hours were compared. Results There were no significant differences among these 3 groups in age, sex and clinical manifestations （vomiting times, diarrhea frequency, dehydration and mental state）. 2 days after treatment, character and frequency of the stools, vomiting times in Group C were significantly better than Group A and B （P 〈 0.05）, there were no significant difference in frequency of stools and vomiting between Group A and B. 4 days after treatment, all patients in three groups turned better, there were no difference among character and frequency of the stools, vomiting times （P 〉 0.05）, but Group C had a higher significant efficiency in 72 hours than Group A and B. Conclusion Low osmolarity ORS, together with smecta, can relieve vomiting, and decrease stool frequency, have a higher significant efficiency.
出处
《中国血液流变学杂志》
CAS
2015年第2期204-207,共4页
Chinese Journal of Hemorheology
基金
益普生腹泻基金
