摘要
目的:对早期先兆流产的患者进行血清β-h CG及孕酮指标的检测,探讨其对保胎治疗的临床指导意义。方法:选取2013年1月-2014年12月本院接诊的84例早孕先兆流产患者以及同期健康体检的42例孕妇作为研究对象,依据保胎治疗后的妊娠结局将其分为继续妊娠组、流产组以及正常对照组各42例。所有患者均采用放射免疫分析法进行血β-h CG的检测,并采用电化学发光法技术进行及孕酮的检测,根据指标水平给予相应的药物保守治疗。结果:治疗前,继续妊娠组与流产组的β-h CG及孕酮指标均低于正常对照组,继续妊娠组低于流产组,组间比较差异均有统计学意义(P<0.05)。继续妊娠组的β-h CG≥5000 m IU/m L以及P≥30 ng/m L的占比59.5%、90.5%均高于流产组的0、11.9%,组间比较差异均有统计学意义(字2=35.593、51.887,P<0.05)。单独检测的诊断正确率57.1%明显低于联合检测的77.4%,组间比较差异有统计学意义(字2=7.812,P<0.05)。结论:孕早期行血β-h CG及孕酮的检测可提高预测先兆流产的准确率,且能为保胎治疗提供较高的治疗意义,提高孕妇的保胎成功率,是一种值得在临床中推广使用的诊断方法。
Objective： To early threatened abortion patients for the detection of serum beta h CG and progesterone index and to discuss the clinical significance of tocolytic therapy. Method： 84 cases of threatened abortion and healthy in the same period of 42 cases of pregnant women from January 2013 to December 2014 in our hospital admissions were selected as the research object, according to the tocolytic therapy after pregnancy outcome, they were divided into ongoing pregnancy, abortion group and normal control groups. All patients were detected by radioimmunoassay method, and the beta h CG was detected by using the method of electrochemical luminescence and the detection of progesterone. Result： The beta h CG and progesterone index of ongoing pregnancy group and abortion group of were significantly lower than the normal control group, beta h CG and progesterone index of ongoing pregnancy group was significantly lower than that of abortion group. The difference between the two groups had statistical significance（P〈0.05）. Ongoing pregnancy group h CG was more than or equal to 5000 m IU/m L and P was greater than or equal to 30 ng/m L for than 59.5%, 90.5% were significantly higher than 0, 11.9% in abortion group, the difference between the two groups had statistical significance（ 字2=35.593, 51.887, P〈0.05）. Separate detection diagnosis correct rate of 57.1% was significantly lower than 77.4% of the combined detection, the difference between the two groups with statistical significant（ 字2=7.812, P〈0.05）. Conclusion： Early pregnancy, serum beta h CG and progesterone detection can improve the accuracy of threatened abortion, miscarriage treatment provide higher therapeutic significance, improve the pregnant women of the success rate of miscarriage.
出处
《中国医学创新》
CAS
2015年第33期67-70,共4页
Medical Innovation of China
基金
2015年江西省卫生厅科研计划(普通)课题(20154035)
关键词
早孕
血Β-HCG
孕酮
保胎
Early pregnancy
Serum β-hCG
Progesterone
Miscarriage
