摘要
目的分析血清pHCG及孕酮检测在先兆流产中的临床应用价值。方法选取2007年1月-2012年12月在本院就诊的早孕患者90例，将孕期4-6周的孕妇作为研究对象，按其临床表现分为正常妊娠组、先兆流产组和流产组，每组各30例，在妊娠第4、5、6周，测定和比较3组孕妇血清孕酮和β-人绒毛膜促性腺激素（β—HCG）水平。结果在妊娠第4、5、6周，3组孕妇孕酮水平差异有统计学意义（组问差异P〈0．05），流产组显著低于先兆流产组（P〈0．05），先兆流产组显著低于正常妊娠组（P〈0．05），而不同时点孕酮水平的差异无统计学意义（组内差异P〉0．05）；3组孕妇之间、不同时点之间β-HCG水平差异和不同组与不同时点的交互作用差异均有统计学意义（组间差异、组内差异、交互作用P均〈0．05），流产组孕妇β-HCG水平显著低于先兆流产组（P〈0．05），先兆流产组显著低于正常妊娠组（P〈0．05）。结论在妊娠早期，血清孕酮和β-HCG水平可作为反映胎儿状态和胎盘功能的重要指标以及早期诊断先兆流产的辅助指标，对孕妇血清孕酮和β-HCG水平的监测具有十分重要的临床意义。
Objective To explore the clinical value of serum β-HCG and progesterone de- tections in treatment of patients with threatened abortion. Methods 90 pregnant women with the Pregnant time of 4 to 6 weeks were selected and divided into the normal pregnancy group, the threatened abortion group and the abortion group according to their clinical manifestations, 30 cases in each group. At 4th, 5th, 6th week of the pregnancy, the serum progesterone and beta human chorionic gonadotropin （beta-HCG） levels were measured and compared in all the pregnant women. Results At 4th, 5th, 6th week of the pregnancy, there was significant difference of the serum progesterone level among three groups （P 〈 0.05）. The serum progesterone level in the abortion group was significantly lower than that in the threatened abortion group （P 〈 0.05）, and the serum progesterone level in the threatened abortion group was significantly lower than that in the normal pregnancy group （P 〈 0.05）. At 5th, 6th week of pregnancy, the β-HCG level of the pregnant women in the abortion group was significantly lower than that in the threatened abortion group （P 〈 0.05）, and the β-HCG level in the threatened abortion group was significantly lower than that in the normal pregnancy group （P 〈 0.05）. Conclusion In early pregnancy, the serum progesterone and β-HCG levels can be used as the auxiliary indexes to reflect the state of fetal, placental function and the early diagnosis of threatened abortion. Monitoring of the serum progesterone and β-HCG levels in the pregnant women is very important in clinic.
出处
《实用临床医药杂志》
CAS
2014年第3期113-115,共3页
Journal of Clinical Medicine in Practice
关键词
先兆流产
孕酮
Β-HCG
临床诊断
threatened abortion
progesterone
β-HCO
clinical diagnosis
