摘要
目的 研究不同大小范围的颈动脉斑块对冠状动脉扩张（CAE）的影响及两者之间的相关性。方法 对2012年12月~2014年12月,在我院行冠脉造影（Coronary Angiography,CAG）和颈动脉超声检查的患者的资料进行回顾性分析。共有入选患者80例,按照是否合并颈动脉斑块分为单纯冠状动脉扩张组（n=34）和冠状动脉扩张合并颈动脉粥样斑块组（n=46）,通过多元线性回归分析,年龄、性别、血脂水平、吸烟史、高血压病和糖尿病史等与CAE的相关性,进一步分析颈动脉斑块的大小和范围与冠状动脉扩张及冠脉病变支数的关系。结果 CAE发生率与性别、血脂水平密切相关（P〈0.05）;男性是CAE的独立危险因素（OR=2.53;95%CI：1.34~2.57）。与颈动脉斑块1级组比较,颈动脉斑块2级和3级斑块组冠脉扩张程度均增高（P〈0.05）。结论 CAE患者常合并有颈动脉斑块,更好发于男性;颈动脉斑块与冠状动脉的扩张之间存在相关性,颈动脉斑块的范围越广泛冠状动脉扩张越严重。
Objective To study the correlation between carotid atheroselerotic plaques and the different size ranges of coronary artery dilation （CAE）. Methods We retrospectively analyzed the patients who underwent coronary angiography and carotid ultrasonography in our hospital from December 2012 to December 2014. According to the patients with or without carotid artery plaque, they were divided into a simple coronary artery dilatation group （ n = 34） and a coronary artery dilatation with carotid artery plaque group （ n = 46 ） , and 80 patients were enrolled and included. After the relations between age, gender, blood lipid levels, smoking history, hypertension and diabetes with CAE were analyzed, we further analyzed the relationship of carotid artery plaque and coronary artery dilatation and severity of coronary lesions. Results There were significant correlations between age, gender, blood lipid levels and CAE （ P 〈 0. 05 ）. The gender of male was an independent risk factor for the development of CAE （ OR = 2. 53 ; 95% CI： 1.34 -2. 57）. Compared with carotid artery plaque 1 group, carotid artery plaque 2 and 3 coronary dilatation were increased （P 〈 0. 05 ）. Conclusion CAE may be associated with carotid plaques frequently, and males are more susceptive. There, is a correlation between the carotid artery atheroselerosis and coronary artery dilation： the wider the range of carotid artery is, the more serious coronary artery expansion.
出处
《现代医院》
2016年第1期24-27,共4页
Modern Hospitals
基金
东莞市医疗卫生类科研一般项目(编号:201410515000083)
关键词
冠状动脉扩张
颈动脉斑块
相关性
Dilatation of Coronary Artery
Carotid Plaque
Con＇elation
