摘要
目的研究60岁以上老年人不同程度颈动脉粥样硬化与冠状动脉病变严重程度的关系。方法对185例老年患者行颈动脉彩色多普勒超声检查、冠状动脉造影或64排双源CT冠状动脉造影检查。分析颈动脉血流动力学与冠脉病变支数的关系及颈动脉斑块严重程度分级与冠脉狭窄指数、冠脉病变支数的关系。结果与无冠脉病变组比较,多支冠脉病变组双侧颈总动脉内径增宽(P<0.05);双颈内动脉最大血流速度增快(P<0.05);双椎动脉阻力指数明显增高(P<0.01)。与无冠脉病变组比较,3个冠脉病变组双颈总动脉阻力均增高(P<0.05)。与颈动脉0级组比较,颈动脉2级和3级斑块组冠脉狭窄指数均增高(P<0.01)。3级颈动脉斑块组100%有冠脉狭窄,颈动脉2级、3级斑块组患者冠状动脉2支以上病变患者明显增加(P<0.01)。结论颈动脉管腔内径增大,血管最大血流速度增快和动脉阻力指数增高与冠状动脉粥样硬化程度密切相关,随着颈动脉粥样硬化程度的增高,冠状动脉狭窄发生率增高,冠脉病变支数增多,血管狭窄程度更严重。
Objective To explore the relationship between the degree of carotid artery atherosclerosis and coronary artery lesion in elderly patients （〉60years）. Methods The color dopper uhrasonography of carotid artery, coronary arteriography or dualsource sixty-four slice CT coronary angiography were performed in 185 elderly patients. The relationships between the haemodynam- ics of carotid artery and branches of coronary artery lesion and between the grades of carotid artery plaque and coronary stenosis index,as well as branches of coronary artery lesion were analyzed. Results The lumen diameter of common carotid artery was extended（P〈0.05） ,the peak velocity of intermal carotid artery was higher（P〈0.05）and blood vessel resistance of arteriae vertebralis was raised（P〈0.01 ）in multi-coronary vessel lesion group than that in non-coronary vessel lesion group. The blood vessel resistance of common carotid artery was higher in 3 groups of coronary artery lesion than non-coronary vessel lesion group （P〈0.05 ）. The coronary artery stenosis index was obviously higher（P〈0.01 ）in 2 grade of carotid artery plaque group and 3 grade group than no plaque group. There were coronary artery lesion in all patients of 3 grade plaque group. The patients in coronary artery lesion not less than 2 branches were increased in 2 grade and 3 grade of carotid artery plaque （P〈0.01）. Conclusions There was a close correlation between coronary artery atherosclerosis and extended lumen diameter,higher the peak velocity and raised blood vessel resistance of carotid artery. As the damage of carotid artery atherosclerosis increasing,the branches and lesion severity of coronary artery increased.
出处
《中华保健医学杂志》
2009年第3期186-188,179,共4页
Chinese Journal of Health Care and Medicine
关键词
颈动脉粥样硬化
冠状动脉
冠状动脉造影
颈动脉超声
冠脉狭窄指数
Carotid artery atherosclerosis
Coronary artery
Coronary angiography
Carotid artery ultrasound
Coronary stenosis index
