摘要
目的 :探讨血清尿酸水平是否与冠心病相关。方法 :经冠状动脉造影确诊的冠心病患者98例和非冠心病患者72例。分别测定血清尿酸及血脂水平。结果 :冠心病患者血清尿酸水平显著高于对照组 (P<0.01) ,相关分析显示血清尿酸水平与冠脉狭窄指数、年龄、甘油三酯、低密度脂蛋白胆固醇、体质量指数呈正相关 (P<0.05或P<0.01)。多因素回归分析显示 ,血清尿酸与冠心病的发生和冠脉狭窄指数无明显相关。结论 :高尿酸血症不是冠心病的独立危险因素。
Objective:To explore the association of serum uric acid with coronary heart disease(CHD).Methods:Ninety-eight patients with CHD proved by angiography and72control subjects without CHD were included in this study,and serum uric acid and blood lipid were determined.Results:Serum uric acid level in CHD patients was markedly higher compared with that in control subjects(P<0.01).Correlation analysis reˉsults showed that serum uric acid level was positively and significantly related to coronary stenosis index,age,lnTG,LDL-C,and body mass index(P<0.05or P<0.01,respectively).Analyzed with multivariate Logistic and stepwise regression analysis,serum uric acid did not have obvious relation with the occurrence of CHD and coronary stenosis index.Conclusion:Elevated serum uric acid is not an independent risk factor for CHD.
出处
《天津医药》
CAS
北大核心
2004年第6期330-332,共3页
Tianjin Medical Journal
关键词
血清
尿酸
冠心病
危险因素
uric acid coronary disease risk factors
