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高尿酸血症与冠心病的相关性研究 被引量:4

STUDY OF CORRELATION BETWEEN HYPERURICEMIA AND CORONARY HEART DISEASE
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摘要 目的探讨高尿酸血症与冠心病的相关性。方法选择冠心病患者180例,分为急性冠脉综合征组及稳定型心绞痛组,另设对照组150例。分别测定血清尿酸、血糖以及血压、体重指数(BMI)、血脂水平。结果冠心病患者尤其是急性冠脉综合征患者血清尿酸水平与对照组相比,有统计学显著意义(P<0.01),相关分析提示血清尿酸水平与冠心病显著相关。结论高尿酸血症是冠心病尤其是急性冠脉综合征的危险因素之一。 Objective To determine the relationship between hyperuricemia and coronary artery disease(CAD). Methods Serum concentration of uric acid was measured and other biochemical assessments such as serum level of Glucose, TG,TC,LDL-c, HDC-c were determined at a fasting state in 180 patients who have undergone coronary angiography. Results Serum level of uric acid in CAD group was significantly higher than that in normal coronary artery group. Correlation analysis results showed that serum uric acid level was positively and significantly related to CAD age.Glucose, TG, LDL-c and body mass index (P 〈 0.05 or P 〈 0.01 ,respectively). Serum uric acid level hears an intimate relationship with the occurrence of CHD.
出处 《老年医学与保健》 CAS 2006年第1期34-35,45,共3页 Geriatrics & Health Care
关键词 高尿酸血症 冠状动脉疾病 危险因素 Hyperuricemia Coronary disease Risk factors
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参考文献7

  • 1Wannamethee SG,Shaper AG,Whincup P.Serum urate and the risk of major coronary heart disease events.Heart,1997,78:147~153. 被引量:1
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二级参考文献6

  • 1Ross R. The pathogenesis of atherosclerosis. In:Eugene Braunwald, ed. Heart disease:A textbook of cardivascular medicine.5th ed. Philadelphia:Saunders, 1999; 1 105-126 被引量:1
  • 2Culleton BF, Larson MG, Kannel WB, et al. Serum uric acid and risk for cardiovascular disease and death: The Framingham Heart Study . Ann Intern Med, 1999, 131: 7-13 被引量:1
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  • 4Freedman DS, Williamson DF, Genter EW, et al. Relation of serum acid to mortality and ischemic heart disease: The NHANESI Epidemiologic Follow-up study. Am J Epidemiol, 1995, 141: 637-644 被引量:1
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  • 6Fang J, Alderman MH. Serum uric acid and cardiovascular mortality: The NHANESI epidemiologic follow-up study, 1971-1992. JAMA, 2000, 283: 2 404-410 被引量:1

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