摘要
目的探讨Ⅱ型糖尿病（T2DM）脑梗死患者发生院内肺部感染的流行病学调查及其影响因素。方法分析入住我院的480例T2DM脑梗死患者的临床资料,其中合并院内肺部感染患者60例,进行流行病学调查,然后分别采用Pearson单因素与多元Logistic回归分析对影响T2DM脑梗死合并院内肺部感染的相关因素进行分析。结果 1 T2DM脑梗死合并院内肺部感染率有一定的流行病学分布特征,与患者年龄、性别、糖尿病病程、BMI、城乡分布、职业、文化程度相关,与入院空腹血糖（FPG）无关;2经Pearson单因素与多元Logistic回归分析,最终确定影响T2DM脑梗死患者并发院内肺部感染的相关因素为：年龄（β=0.273,S.E=0.054,Wald=5.662,OR=1.593,95%CI为1.272~1.872,P〈0.05）、意识障碍（β=0.781,S.E=0.065,Wald=6.657,OR=1.213,95%CI为1.114~1.508,P〈0.05）、合并慢性疾病（β=0.952,S.E=0.040,Wald=7.937,OR=1.608,95%CI为1.411~1.972,P〈0.05）、球麻痹症状（β=0.405,S.E=0.052,Wald=6.334,OR=1.928,95%CI为1.771~2.334,P〈0.05）。结论 T2DM脑梗死合并院内肺部感染具有一定的流行病学分布特征,其发病受年龄、意识障碍、合并慢性疾病及球麻痹症状等因素的影响,应采取有效措施对其加以预防。
Objective To investigate the epidemiological situation and influencing factors of cerebral infarction in patients with type II diabetes mellitus（ T2DM） and nosocomial pulmonary infection. Methods The clinical data of 480 T2 DM patients with cerebral infarction from August 2010 to December 2014 was retrospectively analyzed in our hospital,of whom 60 patients were merged with nosocomial pulmonary infection,and they were firstly given epidemiological survey. Pearson Univariate and Multivariate Logistic regression analysis were used to analyze the relevant factors of cerebral infarction of T2 DM patients with nosocomial pulmonary infection. Results（ 1） The cerebral infarction patients with T2 DM and nosocomial pulmonary infection had some epidemiological distribution,and it was correlated with their age,sex,duration of diabetes,BMI,urban and rural distribution,occupation,and education level,but it was not correlated with fasting plasma glucose（ FPG） on admission.（ 2） Pearson univariate and multivariate Logistic regression analysis showed the influencing factors of cerebral infarction patients with T2 DM and nosocomial lung infection included age（ β = 0. 273,SE = 0. 054,Wald = 5. 662,OR = 1. 593,95% CI = 1. 272 ~1. 872,P〈0. 05）,consciousness（ β = 0. 781,SE = 0. 065,Wald = 6. 657,OR = 1. 213,95% CI = 1. 114 ~1. 508,P〈0. 05）,chronic disease（ β = 0. 952,SE = 0. 040,Wald = 7. 937,OR = 1. 608,95% CI = 1. 411 ~1. 972,P〈0. 05）,and palsy symptoms（ β = 0. 405,SE = 0. 052,Wald = 6. 334,OR = 1. 928,95% CI = 1. 771 ~2. 334,P〈0. 05）. Conclusion The cerebral infarction patients with T2 DM and nosocomial pulmonary infection show certain epidemiological distribution,and the incidence of cerebral infarction is correlated with age,disturbance of consciousness,chronic diseases and symptoms of palsy,which should be taken effective measures to prevent it.
出处
《临床肺科杂志》
2016年第2期296-299,共4页
Journal of Clinical Pulmonary Medicine
关键词
Ⅱ型糖尿病
脑梗死
肺部感染
影响因素
type Ⅱ diabetes
infarction
pulmonary infection
influencing factors
