摘要
目的探讨急性脑卒中患者肺部感染的病原菌分布并分析其危险因素。方法采用病例对照研究的方法,以医院神经内科2008年10月-2011年5月住院脑卒中合并肺部感染的90例患者为病例组,对照组为同期住院无肺部感染的脑卒中患者220例;根据痰培养结果分析病原菌,采用logistic回归分析分析急性脑卒中患者肺部感染的危险因素。结果送检标本192份,检出病原菌100株,检出率52.08%,其中革兰阴性菌占72.00%,革兰阳性菌占20.00%,真菌占8.00%;多因素分析显示,吞咽困难、侵入性操作、住院时间长、意识障碍是急性脑梗死患者合并肺部感染的危险因素,其OR值分别为4.99、4.16、4.55及2.58。结论应依据病原菌特点合理用药,针对危险因素采取有效预防措施。
OBJECTIVE To discuss the distribution of pathogenic bacteria causing pulmonary infections in acute stroke patients and analyze the risk factors. METHODS By means of case-control study, a total of 90 acute stroke patients with pulmonary infections who enrolled in neurology department from Oct 2008 to May 2011 were selected as the study group, meanwhile, totally 200 stroke patients without pulmonary infections were set as the control group; the pathogens were identified through sputum culture result, logistic regression analysis was performed to analyze the risk factors for the pulmonary infections in acute stroke patients. RESULTS Of 192 samples submitted, there were 100 strains of pathogens isolated with the detection rate of 52.08%, including gram-negative bacteria （72.00%）, gram-positive bacteria （20.00%）, and fungi （8.00%）; multivariate factors analysis showed that dysphagia, invasive operation, long hospital stay, and disturbance of consciousness were the risk factors for pulmonary infections in the acute stroke patients, their OR value were 4.99, 4.16, 4.55, and 2.58, respectively. CONCLUSION The antibiotics should be used reasonably on the basis of characteristics and effective measures should be adopted in accordance with the risk factors.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2012年第16期3484-3485,共2页
Chinese Journal of Nosocomiology
关键词
脑卒中
肺部感染
危险因素
Stroke
Pulmonary infection
Risk factors
