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腹腔镜阑尾切除术与开腹阑尾切除术对肠道屏障功能的影响 被引量:1

Influence of laparoscopic appendectomy and open appendectomy on gut barrier function
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摘要 目的比较腹腔镜阑尾切除术与开腹阑尾切除术对肠道屏障功能影响的差异。方法选取2013年6月~2015年5月本院收治的80例阑尾炎患者作为研究对象,按照随机数字表法分为L组和O组,各40例。L组给予腹腔镜阑尾切除术,O组给予开腹阑尾切除术。比较两组术前1 d、术后1 d的血浆D-乳酸和二胺氧化酶(DAO)水平以及术后肠蠕动恢复时间、住院时间、并发症发生率。结果 L组术后1 d的血浆D-乳酸和DAO水平显著低于术前1 d及O组,差异有统计学意义(P〈0.01)。L组的术后肠蠕动恢复时间和住院时间显著短于O组,差异有统计学意义(P〈0.01)。L组的术后肠梗阻、腹腔脓肿和切口感染发生率显著低于O组,差异有统计学意义(P〈0.05)。结论腹腔镜阑尾切除术对肠道屏障功能的损伤轻于开腹阑尾切除术。 Objective To compare the influence of laparoscopic appendectomy and open appendectomy on gut barrier function.Methods 80 patients with appendicitis from June 2013 to May 2015 in our hospital were selected and divided into group L and group O according to random number table method,40 patients in each group.Group L was treated with laparoscopic appendectomy,group O was treated with open appendectomy.The level of D-lacate and plasma diamine oxidase(DAO)before surgery at 1 day and after surgery at 1 day,postoperative bowel recovery time,hospitalization time,the incidence rate of complication in the two groups was compared respectively.Results The level of D-lacate and DAO after surgery at 1 day in group L was lower than that before surgery at 1 day and in group O,with significant difference(P0.01).Postoperative bowel recovery time and hospitalization time in group L was shorter than that in group O,with significant difference(P0.01).The incidence rate of postoperative intestinal obstruction,abdominal abscess and incision infection in group L was lower than that in group O,with significant difference(P0.05).Conclusion The damage of intestinal barrier function in laparoscopic appendectomy is less than that in open appendectomy.
出处 《中国当代医药》 2015年第36期23-25,共3页 China Modern Medicine
基金 广东省汕头市医疗科技计划项目(201509)
关键词 腹腔镜阑尾切除术 阑尾切除术 肠道屏障功能 Laparoscopic appendectomy Open appendectomy Gut barrier function
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