摘要
目的:探讨腹腔镜和开腹结直肠癌手术两种术式对患者肠道屏障功能的影响。方法:选取2007年4月-2011年10月笔者所在医院院普外科行结直肠癌手术的72例患者作为研究对象,其中腹腔镜手术(腹腔镜组)患者34例,开腹手术(开腹组)患者38例。分别于术前1天、术后第1天和术后第3天抽取两组患者静脉血5ml,对血浆D-乳酸水平和血浆二胺氧化酶(DAO)活性进行检测,并对检测结果进行比较分析。结果:两组患者术前血浆D-乳酸水平、血浆DAO活性比较差异无统计学意义(P>0.05);术后第1天、第3天腹腔镜组血浆D-乳酸水平、DAO活性低于开腹组,比较差异有统计学意义(P<0.05)。结论:研究显示对于结直肠癌患者,腹腔镜手术对肠道屏障功能的损伤轻于开腹手术。
Objective ：To investigate the resuhs of laparoscopic and open colorectal cancer surgery on gut barrier function in patients.Methods ：In our hospital from April 2007 to October 2011, 72 cases colorectal cancer patients were selected, including 34 patients with laparoscopic surgery （laparoscopic group）, laparotomy （laparotomy group） of 38 patients.5 ml venous blood s^imples were taken at 1 day before surgery, 1 and 3 days after to detection and analysis. Results ：1 day before surgery, there was no statistical significance in the plasma D-lactate level and patients plasma DAO activity between 2 groups（P〉0.05） ; 1 and 3 days after surgery, plasma D-lactate levels and plasma DAO activity in laparoseopic group was lower than the laparotomy group, were statistically significant differences（P〈0.05）.Conclusion ：Research shows that colorectal cancer patients, laparoscopic surgery for intestinal barrier function is damaged more seriously than open surgery.
出处
《中外医学研究》
2012年第21期11-12,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
