摘要
为了研究牛筋果（Harrisonia perforate）枝叶的化学成分,通过采用硅胶、ODS、Sephadex LH-20等柱色谱和制备液相等各种色谱方法对其95%乙醇提取物进行系统的分离和纯化,共得到了6个化合物,根据理化性质和现代波谱技术分别鉴定为harriperfin E（1）、kihadanin A（2）、kihadanin B（3）、6α-acetoxyobacunol acetate（4）、gardaubryone C（5）和β-sitosterol methyl ether（6）。其中化合物1为一新的色原酮化合物,化合物2~6为首次从该植物中分离得到。
This study was performed to investigate the chemical constituents in the twigs and leaves of Harrisonia perforate. Six compounds were isolated from the 95% EtOH extract of the twigs and leaves of Harrisonia perforate by silica gel, ODS, Sephadex LH-20 column chromatographies and preparative HPLC. On the basis of chemical properties and spectra data, these compounds were identified as harriperfin E （1）, kihadanin A （2）, kihadanin B （3）, 6a-acetoxyobacunol acetate （4）, gardaubryone C （5）, and fl-sitosterol methyl ether （6）, respectively. Compound 1 is a new chromone, and compounds 2-6 are isolated from this plant for the first time.
出处
《药学学报》
CAS
CSCD
北大核心
2015年第12期1622-1624,共3页
Acta Pharmaceutica Sinica
基金
国家科技支撑计划资助项目(2012BAI29B09)
港澳台科技合作专项资助项目(2013DFM30080)
教育部世纪优秀人才计划资助项目(NCEF-12-0676)
关键词
牛筋果
化学成分
色原酮
柠檬苦素类
Harrisoniaperforate
chemical composition
chromone
limonoids
