摘要
目的探讨脑卒中高危人群发生非痴呆性血管性认知功能障碍的危险因素。方法选取脑卒中高危人群715例为研究对象,根据是否发生非痴呆性血管性认知功能障碍分为认知障碍组和认知正常组。其中认知障碍组183例,认知正常组532例,对2组患者的临床资料进行统计和比较,并行Logistic回归分析。结果其中认知障碍183例,男性、年龄≥65岁、高中及以下文化程度、有脑卒中史、合并高脂血症以及高同型半胱氨酸血症者分别占57.38%、60.66%、86.89%、33.88%、68.85%和63.93%,认知正常者532例,上述因素分别占46.05%、39.66%、75.00%、21.62%、55.08%和53.57%,认知障碍组所占比例明显高于认知正常组,2组比较差异有统计学意义(P<0.05)。经Logistic回归分析,高中以下文化程度及合并高脂血症是脑卒中高危人群发生非痴呆性血管性认知功能障碍的独立危险因素(P<0.05)。结论我们对于高脂血症患者应积极控制血脂,并鼓励脑卒中高危人群在日常生活中多学习,加强用脑,减少非痴呆性血管性认知功能障碍的发生。
Objective To investigate risk factors in non‐dementia vascular cognitive impairment patients with high risk of stroke in order to take appropriate measures for prevention.Methods 715 cases with high risk of stroke were selected as re‐search subjects and were divided into cognitive impairment group（n= 183） and normal cognition group（n= 532） based on whether patients had non‐dementia vascular cognitive impairment or not. And then the clinical data in two groups were com‐pared statistically by Logistic regression analysis. Results All 183 cases in cognitive impairment group ,the percent of male , age≥65 years old ,patients with high school education or less ,history of stroke ,hyperlipidemia and high homocysteine sepa‐rately accounted for 57.38% ,60.66% ,86.89% ,33.88% ,68.85% and 63.93% ;Meanwhile ,all 532 cases in normal cogni‐tion group , the above‐mentioned factors respectively accounted for 46.05% ,39.66% ,75.00% ,21.62% ,55.08% and 53.57%. As a result ,it was obviously that the cognitive impairment group had higher proportion than normal cognition group , the difference was statistically significant （P〈0.05）. Logistic regression analysis indicated that high school or less education and hyperlipidemia were independent risk factors in non‐dementia vascular cognitive impairment patients with high risk of stroke （P〈0.05）.Conclusion Cholesterol should be under control in patients with hyperlipidemia ,and we should encourage patients with the high risk of stroke to learn more acknowledge and strengthen mental activities in their daily life in order to re‐duce the incidence of non‐dementia vascular cognitive impairment.
出处
《中国实用神经疾病杂志》
2015年第22期5-7,共3页
Chinese Journal of Practical Nervous Diseases
