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急性早幼粒细胞白血病所致脑梗死1例报道并文献复习 被引量:4

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摘要 目的探讨急性早幼粒细胞白血病所致脑梗死患者的发病机制及临床特点。方法对1例以急性早幼粒细胞白血病为病因的脑梗死患者的诊治过程进行报道,并结合相关文献分析急性早幼粒细胞白血病所致脑梗死的发病机制及临床特点。结果脑梗死以急性早幼粒细胞白血病作为病因较少见,除了神经功能缺损的表现,还有凝血功能障碍的表现,发病机制包括肿瘤细胞淤积造成血管阻塞、促凝物质的表达增加、凝血级联反应的激活、血浆P-选择素的活性增强等。结论应提高对以急性早幼粒细胞白血病为病因的脑梗死的认识,详细的病史和辅助检查有助于早期诊治,尤其是缺乏常见危险因素的年轻脑梗死患者,以免延误诊治。
出处 《卒中与神经疾病》 2015年第5期295-298,共4页 Stroke and Nervous Diseases
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