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急性淋巴细胞白血病化疗合并脑梗死1例报告并文献复习 被引量:3

A case report of acute lymphoblastic leukemia with cerebral infarction and relevant literature review
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摘要 目的加强对急性淋巴细胞白血病患儿治疗过程中合并血栓栓塞性疾病的认识。方法对1例急性淋巴细胞白血病治疗过程中出现大面积脑梗死患儿的临床资料进行回顾性分析。结果脑梗死发生后做抗凝血酶Ⅲ检测,其水平明显下降。而发病前的凝血功能5项检测不能反映高凝状态。该患儿梗死面积广泛,合并枕骨大孔疝,最终死亡。结论应加强并深化急性淋巴细胞白血病患儿凝血功能的监测,以早期识别,及时防治血栓栓塞性疾病。 Objective Recognition about thromboembolism(TE) during therapy of children acute lymphoblastic leukemia should be enhanced. Method Retrospectively analyse the clinical materials of a case of cerebral infarction during therapy of children acute lymphoblastic leukemia. Result Antithrombin m was tested at a low level when cer- ebral infarction occurred, but routine coagulation function test didn' t show hypercoagulative state. The child even- turally died because of the extensive infarction area and eerebellar tonsillar hernia. Conclusion Monitoring of coagulation function should be enhanced and furtheranced, in order to timely recognize, prevent and treat TE.
出处 《中国医刊》 CAS 2014年第1期31-33,共3页 Chinese Journal of Medicine
关键词 急性淋巴细胞白血病 血栓栓塞性疾病 脑梗死 易栓症 Acute lymphoblastie leukemia Thromboembolism Cerebral infarction Thrombophilia
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