摘要
目的探究内镜黏膜剥离术(ESD)治疗消化道肿瘤的临床效果及安全性。方法将41例接受ESD治疗的消化道肿瘤患者设为ESD组,并将同期接受内镜黏膜切除术(EMR)的36例消化道肿瘤患者作为对照组。比较2组患者的病灶大小、手术时间、病灶切除情况以及相关并发症的发生情况。结果 2组病灶平均直径、病灶大小分布以及手术时间存在显著差异(P<0.05)。ESD组患者的整块切除率为90.24%,其治愈性切除率为80.49%,显著高于EMR组的44.44%和47.22%(P<0.05)。2组患者的纵向及横向切缘阴性率也存在显著差异(P<0.05)。ESD组患者的并发症发生率为7.32%,EMR组患者为11.11%。结论 ESD方案治疗消化道肿瘤,能够一次性切除较大病灶,提高了整块切除率和组织学治愈切除率。
Objective To explore the clinical efficacy and safety of endoscopic submucosal dissection（ ESD） in the treatment of patients with digestive tract tumor. Methods A total of 41 digestive tract tumor patients treated with ESD were designed as ESD group,and 36 digestive tract tumor patients treated with EMR were designed as control group. Size of the lesions,the operation time,and resection of the lesions and the incidence of complications were compared between the two groups. Results There were significant differences in average diameter of the lesions,distribution of lesions and operating time between two groups（ P〈 0. 05）. The whole resection rate and the cure rate of the ESD groups were 90. 24% and 80. 49%,which were significantly higher than 44. 44% and 47. 22% of the EMR group（ P〈 0. 05）. There were significant differences in the negative rates of vertical and lateral margin between the two groups（ P〈 0. 05）. The incidence rate of complications in the ESD group was7. 32%,and the incidence rate of complications in the EMR group was 11. 11%. Conclusion Application of ESD in treating digestive tract tumor can cut off large lesions by one time,improve the whole resection rate and histological resection rate.
出处
《实用临床医药杂志》
CAS
2015年第21期34-37,共4页
Journal of Clinical Medicine in Practice
关键词
内镜黏膜下剥离术
消化道肿瘤
疗效
安全性
endoscopic submucosal dissection
digestive tract tumor
efficacy
safety
