摘要
目的:评价胆舒胶囊联合消炎利胆片治疗肝胆湿热型慢性胆囊炎的临床疗效。方法:选择2013年1月—2014年12月来院治疗的肝胆湿热型慢性胆囊炎的患者84例为研究对象,随机将其分成两组,每组42例。对照组:采用消炎利胆片治疗。观察组:采用消炎利胆片联合胆舒胶囊治疗。观察两组患者疗效及临床症状。结果:观察组总有效率97.62%高于对照组总有效率69.05%,差异具有统计学意义(P<0.01)。观察组B超总有效率95.24%高于对照组B超总有效率61.90%,差异有统计学意义(P<0.01)。治疗后,观察组症状积分(7.48±2.73)分少于对照组症状积分(10.92±3.36)分,差异具有统计学意义(P<0.01)。治疗后,观察组右肋疼痛(1.91±0.86)分、恶心呕吐(1.27±0.34)分、纳呆腹胀(1.30±0.76)分、胆区压痛(1.68±0.94)分、小便黄赤(1.30±0.54)分都低于对照组右肋疼痛(2.37±0.93)分、恶心呕吐(1.69±0.55)分、纳呆腹胀(1.90±0.94)分、胆区压痛(2.27±1.24)分、小便黄赤(1.78±0.70)分,差异均有统计学意义(P<0.01)。治疗后,观察组血清TNF-α(49.48±5.71)ng/L低于对照组血清TNF-α(53.12±7.52)ng/L,差异具有统计学意义(P<0.05)。结论:胆舒胶囊联合消炎利胆片治疗肝胆湿热型慢性胆囊炎疗效显著,能够有效改善患者临床症状。
Objective： To evaluate the curative effect of Danshu Capsule combined with Xiaoyan Lidan Tablets in the treatment of chronic cholecystitis of damp- heat type. Methods： 84 cases of chronic cholecystitis with liver and gallbladder damp- heat type during January 2013- December 2014 in our hospital were randomly divided into two groups,each group42 cases. The control group： Xiaoyan Lidan Tablets. The observation group： Xiaoyan Lidan Tablets combined with Danshu Capsule. We observed the efficacy and clinical symptoms in the two groups. Results： The total effective rate of the observation group was 69. 05% and was higher than that of the control group（ P 〈0. 01）. The total effective rate of B in the observation group was 61. 90% and was higher than that of the control group（ 95. 24%） and the difference was statistically significant（ P 〈0. 01）. After treatment,the symptom score of the observation group（ 7. 48 ± 2. 73） was less than the control group＇s（ 10. 92 ± 3. 36） and the difference was statistically significant（ P 〈0. 01）. After treatment,the right rib pain（ 1. 91 ± 0. 86）,nausea and vomiting（ 1. 27 ± 0. 34）,poor appetite,abdominal distension（ 1. 30 ± 0. 76）,bile area tenderness（ 1. 68 ± 0. 94） and yellow urination（ 1. 30 ± 0. 54） of the observation group were higher than the control group＇s right rib pain（ 2. 37 ± 0. 93）,nausea and vomiting spit（ 1. 69 ± 0. 55）,poor appetite,abdominal distension（ 1. 90 ±0. 94）,bile area tenderness（ 2. 27 ± 1. 24） and urine yellow red（ 1. 78 ± 0. 70）. The differences were statistically significant（ P 〈0. 01）. After treatment,the serum TNF- α（ 49. 48 ± 5. 71） ng / L in the observation group was lower than the control group＇s（ 53. 12 ± 7. 52） and the difference was statistically significant（ P〈 0. 05）. Conclusion： Danshu Capsules combined with Xiaoyan Lidan tablets in the treatment of chronic cholecystitis with damp- heat type has good curative effect and can eff
出处
《中华中医药学刊》
CAS
北大核心
2015年第11期2669-2671,共3页
Chinese Archives of Traditional Chinese Medicine
基金
浙江省医学会临床科研基金项目(2013ZYC-A143)
关键词
胆舒胶囊
消炎利胆片
肝胆湿热型
慢性胆囊炎
Danshu Capsules
Xiaoyan Lidan Tablets
liver and gallbladder damp-heat type
chronic cholecystitis
