摘要
目的了解急性胆囊炎时胆汁中需氧菌感染及其对抗生素的敏感情况,为临床抗感染治疗提供依据。方法对2006年6月—2008年6月我院外科送检的122例急性胆囊炎手术中采集的胆汁进行需氧菌培养和药物敏感试验。结果122例胆汁标本中,有83例(68.03%)检出需氧菌,共分离出92个菌株,其中大肠埃希菌占51.08%,肺炎克雷伯菌占10.87%,粪肠球菌占11.95%。药物敏感试验结果显示,所有菌株存在不同程度的耐药,对青霉素类、头孢菌素类抗生素耐药性较高;革兰阳性菌对万古霉素最为敏感;革兰阴性杆菌对亚胺培南最为敏感。结论对胆汁进行细菌培养和药物敏感试验是很有必要的,为防止滥用抗生素以减少细菌的耐药性,临床应根据实验室的药物敏感试验结果合理选用抗生素。
Objective To contribute the knowledge of bile aerobe infection in acute cholecystitis(AC) and its sensitivity to antibiotics,to provide basis for clinical anti-infective therapy.Methods Bile was collected from 122 AC patients to do aerobe culture and drug sensitivity test(DST).Results In 122 cases of bile samples,positive aerobes were detected out in 83(68.03%);a total of 92 strains were isolated,among which Escherichia coli accounted for 51.08%,Klebsiella pneumoniae 10.87%,Enterococcus faecalis 11.95%.DST results showed that in all bacteria there were varying degrees of drug resistances,relatively higher resistant to penicillin,cephalosporins;Gram-positive bacteria were the most sensitive to vancomycin,but Gram-negative bacilli to imipenem.Conclusion Use of bile is necessary in bacterial culture and DST.Clinical antibiotics choice should be made reasonably based on results of laboratory DST,to prevent the abuse of antibiotics to reduce bacterial resistance.
出处
《中国全科医学》
CAS
CSCD
北大核心
2009年第12期1086-1087,共2页
Chinese General Practice
关键词
胆汁
抗菌药
微生物敏感性试验
Bile
Anti-bacterial agents
Microbial sensitivity tests
