摘要
目的评价T细胞斑点试验在结核性胸膜炎中的诊断价值。方法将2013-01-2014-06收治的渗出性胸膜炎患者311例,分为结核性胸膜炎组182例和非结核性胸膜炎组129例,进行外周血T细胞斑点试验检测。计算T-SPOT.TB试验在结核性胸膜炎诊断中的灵敏度、特异度、阳性预测值、阴性预测值、阳性似然比和阴性似然比。结果 T细胞斑点试验诊断结核性胸膜炎的灵敏度为86.5%,特异度为82.5%,阳性预测值为87.9%,阴性预测值为80.6%,阳性似然比为4.95,阴性似然比为0.16。结论 T-SPOT.TB试验具有较高的灵敏度和特异度,以及快速而准确的特点,在诊断结核性胸膜炎方面有较高临床应用价值。
Objective To evaluate the clinical application value of T cells spot test（ T-SPOT. TB） in diagnosis of tuberculous pleurisy.Methods A total of 311 patients with exudative pleurisy from January 2013 to June 2014 were enrolled in this study,and were divided into： tuberculous pleurisy group（ n = 182） and non-tuberculous pleurisy group（ n = 129）. The peripheral blood T-SPOT. TB was performed in all patients. The sensitivity,specificity,positive predictive value,negative predicative value,positive likelihood ratio and negative likelihood ratio of T-SPOT. TB for tuberculous pleurisy were calculated and recorded. Results T-SPOT. TB yielded the sensitivity of 86. 5%,specificity of 82. 5%,negative predicative value of 87. 9%,negative predicative value of 80. 6%,positive likelihood ratio of 4. 95 and negative likelihood ratio of 0. 16 in diagnosis of tuberculous pleurisy. Conclusion T-SPOT. TB test has a higher value in clinical diagnosis of tuberculous pleurisy with higher sensitivity,specificity and accuracy,and shorter time.
出处
《山西医科大学学报》
CAS
2015年第10期1002-1006,共5页
Journal of Shanxi Medical University
