摘要
目的获得2004年北京市结核分枝杆菌复合菌群耐药性数据。方法对北京市2004年登记菌阳患者分离的结核分枝杆菌复合群,采用WHO/IUATLD规定的1%比例法进行H、R、S和E耐药性检测。结果共纳入1 197例病例,样本总体耐药率是20.1%,MDR耐药率为3.5%,其中初始耐药率为17.9%,初始MDR耐药率为2.3%,获得性耐药率为35.1%,获得性MDR耐药率为11.7%。结论北京市流行的结核分枝杆菌复合群的耐药比例、特别是初治患者的MDR耐药率较低;获得性R耐药与获得性MDR耐药之间存在较高的相关性。
Objective To obtain the data on drug resistances(DR) of Mycobacterium tuberculosis complexes(MTBC) strains isolated from the patients of Beijing in 2004.Methods All new registered bacterium-positive patients were selected in 2004.One percent proportion method was used for drug susceptibility testing of isoniazid,rifampicin,streptomycin and ethambutol,according to the Guidelines for surveillance of drug resistance in tuberculosis of WHO/lUATLD. Results 1197 TB cases were enrolled.The total DR rate was 20.1% and total multi-drug resistance(MDR) was 3.5%.The initial DR rate was 17.9% and initial MDR rate was 2.3%.The acquired DR rate was 35.1% and acquired MDR rate was 11.7%.Conclusions All types of DR rates of MTBC strains isolated from the patients of Beijing were lower than the reports of other provinces of China,especially in the initial MDR rate.There are higher relativity between acquired drug resistance and acquired MDR resistance.
出处
《中国防痨杂志》
CAS
2007年第6期475-478,共4页
Chinese Journal of Antituberculosis
