摘要
目的：探讨T-SPOT.TB诊断艾滋病并肺结核的价值。方法：选取53例艾滋病并肺结核患者作为观察组，46例艾滋病无肺结核患者作为对照组。对两组进行T-SPOT.TB检测。结果：观察组T-SPOT.TB阳性率为81.1%（43/53），显著高于对照组的15.2%（7/46），差异有统计学意义（P〈0.05）。T-SPOT.TB检测艾滋病并肺结核灵敏度为86.0%，特异度为79.6%，阳性预测值为81.1%，阴性预测值为84.8%。观察组CD4＋计数≥200/μl患者T-SPOT. TB阳性率为83.3%（15/18），高于CD4＋计数〈200/μl患者的74.3%（26/35），但差异无统计学意义（P〉0.05）。结论：T-SPOT.TB检测可作为艾滋病并肺结核的有效诊断方法。
Objective：To investigate the value of T-SPOT.TB in diagnosis of AIDS combined tuberculosis.Methods：53 cases of patients with AIDS combined tuberculosis were selected as observation group, and 46 cases of patients with AIDS without tuberculosis were selected as control group. TB were detected in patieuts by T-SPOT.TB method.Results：The T-SPOT.TB positive rate of observation group was 81.1% （43/53）, which was significantly higher than control group [15.2% （7/46）], the difference was statistically significant （P〈0.05）. The sensitivity of T-SPOT.TB diagnosis of AIDS combined tuberculosis was 86.0%, specificity was 79.6%, positive predictive value was 81.1%, and negative predictive value was 84.8%. The T-SPOT.TB positive rate of CD4＋ count ≥200/μl patients in observation group was 83.3% （15/18）, which was higher than CD4^＋ count 〈200 /μl [74.3% （26/35）], but the difference was not statistically significant （P〉0.05）.Conclusions：T-SPOT.TB can be used as effective diagnosis method of AIDS combined tuberculos
出处
《医学检验与临床》
2015年第3期9-10,共2页
Medical Laboratory Science and Clinics
